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1814-64-8

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  • Benzenamine,4-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-

    Cas No: 1814-64-8

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1814-64-8 Usage

Uses

LY-165,163 is a selective 5-HT1A and 5-HT1D serotonin receptor antagonist.

Check Digit Verification of cas no

The CAS Registry Mumber 1814-64-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,1 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1814-64:
(6*1)+(5*8)+(4*1)+(3*4)+(2*6)+(1*4)=78
78 % 10 = 8
So 1814-64-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H22F3N3/c20-19(21,22)16-2-1-3-18(14-16)25-12-10-24(11-13-25)9-8-15-4-6-17(23)7-5-15/h1-7,14H,8-13,23H2

1814-64-8 Well-known Company Product Price

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  • Sigma

  • (S009)  LY-165,163  solid

  • 1814-64-8

  • S009-25MG

  • 1,029.60CNY

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1814-64-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name PAPP

1.2 Other means of identification

Product number -
Other names p-Nh2-pe-tfmpp

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1814-64-8 SDS

1814-64-8Relevant articles and documents

Preparation and biodistribution of -[125I]Iodo-4-aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine and -[125I]Iodo-4-azidophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine

Chumpradit,Kung,Billings,Guo,Wu,Shih

, p. 543 - 547 (2007/10/02)

The iodinated analogue of 1-[2-(4-aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine (PAPP), IPAPP (4), and the corresponding azido compound azido-IPAPP (5) were synthesized. The corresponding no-carrier-added 125I (T( 1/2 ) = 60 days, 35-60 keV) labeled compounds were also prepared. High specific binding was observed from in vitro binding studies using rat brain tissue preparation; K(i) = 20 and 17.5 nM against [3H]-5-HT. In vivo biodistribution studies in rats showed that azido-[125I]IPAPP passed through intact blood-brain barrier and localized in the brain. Ex vivo autoradiography of rat brain sections exhibited a diffuse uptake pattern, which may be due to specific and nonspecific binding. The results indicate that IPAPP and azido-IPAPP may not be suitable to image the serotonin receptor in the brain.

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