2827-49-8

Basic information

• Product Name: 2,4,6-tris(diethylamino)-1,3,5-triazine
• Synonyms: 2,4,6-tris(diethylamino)-1,3,5-triazine;N,N,N',N',N'',N''-Hexaethyl-1,3,5-triazine-2,4,6-triamine
• CAS NO: 2827-49-8
• Molecular Formula: C₁₅H₃₀N₆
• Molecular Weight: 294.4389
• EINECS: 220-590-5
• Mol File: 2827-49-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 422.5°Cat760mmHg
• Flash Point: 209.3°C
• Appearance: /
• Density: 1.043g/cm³
• Vapor Pressure: 2.39E-07mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 2,4,6-tris(diethylamino)-1,3,5-triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-tris(diethylamino)-1,3,5-triazine(2827-49-8)
• EPA Substance Registry System: 2,4,6-tris(diethylamino)-1,3,5-triazine(2827-49-8)

Safety Data

• Hazardous Substances Data: 2827-49-8(Hazardous Substances Data)

Usage

General Description

2,4,6-tris(diethylamino)-1,3,5-triazine, also known as TDATE, is a chemical compound that is commonly used as a crosslinking agent in the production of thermosetting resins and coatings. It is a white, crystalline solid that is soluble in organic solvents. TDATE is highly reactive and can form strong, heat-resistant bonds when mixed with other chemicals. It is often used in the manufacture of adhesives, sealants, and coatings for applications in the automotive, aerospace, and construction industries. TDATE is known to be toxic if ingested or inhaled, and proper handling and safety precautions should be taken when working with this chemical.

InChI:InChI=1/C15H30N6/c1-7-19(8-2)13-16-14(20(9-3)10-4)18-15(17-13)21(11-5)12-6/h7-12H2,1-6H3

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 109-89-7 diethylamine 
• 584-02-1 2-pentanol 
• 121-44-8 triethylamine 
• 84014-81-3 N-(chloroformyl)-N',N'-diethyl-N-methylurea 
• 580-48-3 2-chloro-4,6-bis(diethylamino)-1,3,5-triazine 

Downstream Products

• 109-89-7 diethylamine 
• 108-80-5 isocyanuric acid 

Relevant articles and documents

Synthesis and antiviral evaluation of some C3-symmetrical trialkoxy-substituted 1,3,5-triazines and their molecular geometry

As one of our projects, we here report some new molecular modifications of 2,4,6-trichloro-1,3,5-triazine (TCTAZ: 1) to symmetrical 2,4,6-trialkoxy- or 2,4,6-triaryloxy-substituted 1,3,5-triazine (TAZ) molecules, as well as the results of anti-herpes simplex virus type 1 (anti-HSV-1) activity evaluation of synthesized 2,4,6-trisubstituted TAZ derivatives. Among the tested 2,4,6-trisubstituted TAZ derivatives, we reconfirmed that a C3-symmetrical TAZ derivative, 4e, shows the highest level of anti-HSV-1 activity with a good selectivity index. In this paper, we also report the results of the preparation of newly targeted TAZ derivatives and the structure-activity relationships (SARs) of these trialkoxy-substituted TAZ derivatives and related compounds. The sugar recognition properties of C3-symmetrical TAZ derivative 4e are also described.

Synthesis and cytotoxic activity of trisubstituted-1,3,5-triazines

1,3,5-Triazine derivatives were screened for phototoxicity as well as the cytotoxic activities against leukemia and adenocarcinoma derived cell lines in comparison to the normal human keratinocytes. A simple and environmentally friendly procedure has been developed for the synthesis of 1,3,5-triazine derivatives under microwave irradiation in the presence of a HY zeolite. The catalyst can be recovered and reused. Thus, the procedure provides a simple and green synthetic methodology under environmentally friendly conditions. Structure-activity relationships between the chemical structures and antimycobacterial and photosynthesis-inhibiting activity of the evaluated compounds are also discussed.

4,6-Bis- and 2,4,6-tris-(N,N-dialkylamino)-s-triazines: synthesis, NMR spectra and restricted rotations

Syntheses of various symmetrically and non-symmetrically trisubstituted trazines are reported.Dynamic NMR (1H and 13C) experiments demonstrate that 2,4,6-tris(dialkylamino)-s-triazines show correlated rotations of the alkyl groups in the dialkylamino moieties.Unsymmetrical 2-chloro, 2-alkoxy- and 2-aryloxy-4,6-bis(di-n-alkylamino)-s-triazines display two non-equivalent n-alkyl groups, due to the restricted rotation around the Ar-N bonds.