28334-98-7

Basic information

• Product Name: 5-ethoxyresorcinol
• Synonyms: 5-ethoxyresorcinol;5-Ethoxy-1,3-benzenediol
• CAS NO: 28334-98-7
• Molecular Formula: C₈H₁₀O₃
• Molecular Weight: 154.1632
• EINECS: 248-973-2
• Mol File: 28334-98-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 289.8°C at 760 mmHg
• Flash Point: 129.1°C
• Appearance: /
• Density: 1.215g/cm³
• Vapor Pressure: 0.00124mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: 5-ethoxyresorcinol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ethoxyresorcinol(28334-98-7)
• EPA Substance Registry System: 5-ethoxyresorcinol(28334-98-7)

Safety Data

• Hazardous Substances Data: 28334-98-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H10O3/c1-2-11-8-4-6(9)3-7(10)5-8/h3-5,9-10H,2H2,1H3

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 75-03-6 ethyl iodide 
• 74-96-4 ethyl bromide 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 
• 82547-03-3 2-(3,4-diethoxyphenyl)-3,7-diethoxy-5-hydroxy-4H-chromen-4-one 
• 926-66-9 2-ethoxyprop-1-ene 
• 1663-67-8 malonoyl dichloride 

Downstream Products

• 108-73-6 3,5-dihydroxyphenol 
• 91971-66-3 6-Ethoxy-2,5-dihydroxy-4-methoxy-acetophenon 
• 76554-79-5 1-(2-ethoxy-6-hydroxy-4-methoxy-phenyl)-ethanone 
• 855155-31-6 4-ethoxy-2-hydroxy-6-methoxy-3-methyl-benzaldehyde 
• 99186-87-5 4-ethoxy-2,6-dihydroxy-3-methyl-benzaldehyde 
• 855155-37-2 5-ethoxy-4-methyl-resorcinol 
• 857563-98-5 2,3',4'-triethoxy-6-hydroxy-4-methoxy-deoxybenzoin 
• 856355-09-4 2-ethoxy-4,6-dihydroxy-benzaldehyde 
• 10373-41-8 3,5-diethoxyphenol 
• 91061-74-4 6-Aethoxy-2,4-dihydroxy-acetophenon 
• 857564-00-2 2,3',4'-triethoxy-4,6-dihydroxy-deoxybenzoin 

Relevant articles and documents

BROMODOMAIN INHIBITORS FOR TREATING DISEASE

Disclosed herein are compounds and compositions useful in the treatment of bromodomain-containing protein-mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibiting activity of a bromodomain-containing protein in a human or animal subject are also provided.

Enol Ethers, XIV. Acylation of Keto Enol Ethers with Malonyl Dichloride - A New Synthesis of Phloroglucinols

Phloroglucinols 4 and/or 4-hydroxy-2H-pyran-2-ones 5 are formed from keto enol ethers 1 and malonyl dichloride (2a) in high yields.Since the pyranones 5 can be smoothly converted into phloroglucinols, the reaction of 1 with 2a represents a new, facile synthetic route to phloroglucinols.The reaction proceeds via formation of a chloro carbonyl ketene 8 and its subsequent reaction with 1.The product ratio 4:5 is rationalized in terms of substituent effects in the enol ether substrate.

Process for preparing polyphenols

Polyphenols of the general formula: STR1 wherein R represents a readily cleavable ether group and R' represents a hydrogen atom or a lower alkoxycarbonyl, such as the methoxycarbonyl or ethoxycarbonyl group, and of phloroglucinol, are made by heating a compound of the general formula: STR2 wherein R and R' have the same significance given above, with an alkali metal alcoholate and, if desired, converting the resulting compound of formula I into pholoroglucinol by ether-cleavage and removal of any ester group denoted by R' which may be present in accordance with methods known per se.