2846-62-0

Basic information

• Product Name: (2-Furylmethoxy)trimethylsilane
• Synonyms: (2-Furanylmethoxy)trimethylsilane;(2-Furylmethoxy)trimethylsilane;2-(Trimethylsiloxymethyl)furan;Furfuryloxytrimethylsilane
• CAS NO: 2846-62-0
• Molecular Formula: C₈H₁₄O₂Si
• Molecular Weight: 0
• Mol File: 2846-62-0.mol
• Article Data: 31

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-Furylmethoxy)trimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Furylmethoxy)trimethylsilane(2846-62-0)
• EPA Substance Registry System: (2-Furylmethoxy)trimethylsilane(2846-62-0)

Safety Data

• Hazardous Substances Data: 2846-62-0(Hazardous Substances Data)

Usage

General Description

(2-Furylmethoxy)trimethylsilane, also known as FMOTMS, is a chemical compound that belongs to the family of organosilicon compounds. It is commonly used as a reagent in organic synthesis due to its unique reactivity and ability to functionalize organic molecules. FMOTMS is often used as a silylating agent, meaning it can transfer a silyl group to a target molecule, leading to the creation of new functional groups. This chemical is also known for its use in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of materials with potential applications in electronics and optoelectronics. FMOTMS is a colorless liquid with a sweet, ether-like odor and is typically stored and handled under inert gas conditions due to its sensitivity to moisture and air.

Upstream product

• 98-00-0 (2-furyl)methyl alcohol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 18156-74-6 1-(Trimethylsilyl)imidazole 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 98-00-0 (2-furyl)methyl alcohol 
• 623-17-6 furfurylacetate 

Relevant articles and documents

Reaction of SF4 with alcohols: preparation of 2-(fluoromethyl) furan and 2-fluoro-1-phenylethane

The fluorination of (2-furyl)methanol and 2-phenylethanol with sulfur tetrafluoride is described. The reactions were carried out in glass tubes at -50°C in the presence of triethylamine or pyridine in dichloromethane or cyclohexane solution. The products,

Silylation of Alcohols, Phenols, and Silanols with Alkynylsilanes – an Efficient Route to Silyl Ethers and Unsymmetrical Siloxanes

The formation of several silyl ethers (alkoxysilanes, R3Si-OR') and unsymmetrical siloxanes (R3Si-O-SiR'3) can be catalyzed by the commercially available potassium bis(trimethylsilyl)amide (KHMDS). The reaction proceeds via direct dealkynative coupling between various alcohols or silanols and alkynylsilanes, with a simultaneous formation of gaseous acetylene as the sole by-product. The dehydrogenative and dealkenative coupling of alcohols or silanols are well-investigated, whilst the utilization of alkynylsilanes as silylating agents has never been comprehensively studied in this context. Overall, the presented system allows the synthesis of various attractive organosilicon compounds under mild conditions, making this approach an atom-efficient, environmentally benign, and sustainable alternative to existing synthetic solutions.

Fast and efficient method for Silylation of alcohols and phenols with HMDS in the presence of bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides

Bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides were used efficiently for rapid and efficient trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) in CH3CN. All reactions were carried out at room temperature within immediate-120?min timeframe to afford trimethylsilyl ether derivatives in high to excellent yields. Investigation of the results exhibited that the prepared bis-thiourea metal complexes show the activity as Co(tu)2Cl2> Ni(tu)2Cl2> Cu(tu)2Cl2> Zn(tu)2Cl2 in their silylation reactions.