28669-35-4Relevant academic research and scientific papers
Synthesis of 3 H-1,2,4-Triazol-3-ones via NiCl2-Promoted Cascade Annulation of Hydrazonoyl Chlorides and Sodium Cyanate
Du, Shiying,Yang, Zuguang,Tang, Jianhua,Chen, Zhengkai,Wu, Xiao-Feng
, p. 2359 - 2363 (2021/04/05)
A nickel-promoted cascade annulation reaction for the facile synthesis of 3H-1,2,4-triazol-3-ones from readily available hydrazonoyl chlorides and sodium cyanate has been developed. The transformation occurs through a cascade nickel-promoted intermolecular nucleophilic addition-elimination process, intramolecular nucleophilic addition, and a hydrogen-transfer sequence. The method has been successfully applied for the construction of the core skeleton of the angiotensin II antagonist.
Palladium-Catalyzed cascade carbonylative synthesis of 1,2,4-triazol-3-ones from hydrazonoyl chlorides and NaN3
Du, Shiying,Wang, Wei-Feng,Song, Yufei,Chen, Zhengkai,Wu, Xiao-Feng
, p. 974 - 978 (2021/02/01)
A palladium-catalyzed three-component carbonylative reaction for the synthesis of 3H-1,2,4-triazol-3-ones from hydrazonoyl chlorides and NaN3 has been achieved. The reaction presumably proceeds through a cascade carbonylation, acyl azide format
Green preparation method of 1,2,4-triazol-3-one compound
-
Paragraph 0006; 0032-0038; 0040-0043; 0048-0051, (2021/07/08)
The invention discloses a green preparation method of a 1,2,4-triazol-3-one compound. The green preparation method comprises the following steps: adding a nickel accelerant, triethylamine, chlorohydrazone and sodium cyanate into an organic solvent, conduc
Preparation method of 1,2,4-triazol-3-one compound
-
Paragraph 0032-0037, (2021/03/24)
The invention discloses a preparation method of a 1,2,4-triazol-3-one compound. The preparation method comprises the following steps: adding a palladium catalyst, a ligand, a carbon monoxide substitute, chlorohydrazone and sodium azide into an organic sol
