288615-43-0

Basic information

• Product Name: N-(2-methyl-5-trifluoromethyl-phenyl)-acetamide
• Synonyms: N-(2-methyl-5-trifluoromethyl-phenyl)-acetamide
• CAS NO: 288615-43-0
• Molecular Weight: 217.191
• Mol File: 288615-43-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(2-methyl-5-trifluoromethyl-phenyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-methyl-5-trifluoromethyl-phenyl)-acetamide(288615-43-0)
• EPA Substance Registry System: N-(2-methyl-5-trifluoromethyl-phenyl)-acetamide(288615-43-0)

Safety Data

• Hazardous Substances Data: 288615-43-0(Hazardous Substances Data)

Upstream product

• 65754-26-9 2-methyl-5-trifluoromethylnitrobenzene 
• 25449-96-1 3-amino-4-methylbenzotrifluoride 
• 108-24-7 acetic anhydride 
• 56-23-5 tetrachloromethane 
• 120-66-1 N-(2-methylphenyl)acetamide 

Downstream Products

• 875155-20-7 2-acetylamino-5-nitro-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-21-8 2-acetylamino-5-amino-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-22-9 2-acetylamino-5-[1,2,4]triazol-4-yl-4-trifluoromethyl-benzoic acid 
• 875155-24-1 2-amino-5-[1,2,4]triazol-4-yl-4-trifluoromethyl-benzoic acid methyl ester 
• 288615-45-2 2-amino-5-nitro-4-trifluoromethyl-benzoic acid 
• 875155-27-4 2-isocyanato-5-nitro-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-23-0 2-acetylamino-5-[1,2,4]triazol-4-yl-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-18-3 2-acetylamino-5-nitro-4-trifluoromethyl-benzoic acid 
• 875155-19-4 2-amino-5-nitro-4-trifluoromethyl-benzoic acid methyl ester 
• 288615-44-1 2-Methyl-4-nitro-5-trifluoromethylacetanilide 

Relevant articles and documents

6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists

A new set of quinazolinedione sulfonamide derivatives as competitive AMPA receptor antagonist with improved properties compared to 1 is disclosed. By modulating physico-chemical properties, compound 29 was identified with a low ED50 of 5.5 mg/kg in an animal model of anticonvulsant activity after oral dosage.

Regioselective electrophilic trifluoromethylation of substituted anilines and derivatives in superacid

In a one pot procedure, treatment of chloro or methyl substituted acetanilides in HF/SbF5/CCl4 followed by addition of HF/pyridine yields trifluoromethyl derivatives with high regioselectivity.