875155-19-4

Basic information

• Product Name: Benzoic acid, 2-amino-5-nitro-4-(trifluoromethyl)-, methyl ester
• CAS NO: 875155-19-4
• Molecular Formula: C9H7F3N2O4
• Molecular Weight: 264.161
• Mol File: 875155-19-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 174 - 175 °C
• Boiling Point: 389.1±42.0 °C(Predicted)
• Density: 1.509±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoic acid, 2-amino-5-nitro-4-(trifluoromethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-amino-5-nitro-4-(trifluoromethyl)-, methyl ester(875155-19-4)
• EPA Substance Registry System: Benzoic acid, 2-amino-5-nitro-4-(trifluoromethyl)-, methyl ester(875155-19-4)

Safety Data

• Hazardous Substances Data: 875155-19-4(Hazardous Substances Data)

Upstream product

• 869550-68-5 methyl 2-(acetylamino)-4-(trifluoromethyl)benzoate 
• 67-56-1 methanol 
• 288615-45-2 2-amino-5-nitro-4-trifluoromethyl-benzoic acid 
• 288615-43-0 N-(2-methyl-5-trifluoromethyl-phenyl)-acetamide 
• 25449-96-1 3-amino-4-methylbenzotrifluoride 
• 288615-44-1 2-Methyl-4-nitro-5-trifluoromethylacetanilide 
• 875155-20-7 2-acetylamino-5-nitro-4-trifluoromethyl-benzoic acid methyl ester 

Downstream Products

• 288615-45-2 2-amino-5-nitro-4-trifluoromethyl-benzoic acid 
• 875155-21-8 2-acetylamino-5-amino-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-22-9 2-acetylamino-5-[1,2,4]triazol-4-yl-4-trifluoromethyl-benzoic acid 
• 875155-24-1 2-amino-5-[1,2,4]triazol-4-yl-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-23-0 2-acetylamino-5-[1,2,4]triazol-4-yl-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-27-4 2-isocyanato-5-nitro-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-20-7 2-acetylamino-5-nitro-4-trifluoromethyl-benzoic acid methyl ester 

Relevant articles and documents

6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists

A new set of quinazolinedione sulfonamide derivatives as competitive AMPA receptor antagonist with improved properties compared to 1 is disclosed. By modulating physico-chemical properties, compound 29 was identified with a low ED50 of 5.5 mg/kg in an animal model of anticonvulsant activity after oral dosage.

QUINAZOLINE DERIVATIVES

The present invention relates to 1H-Quinazoline-2,4-dione derivatives of formula (I) wherein the substituents are defined as in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them.