28873-45-2

Upstream product

• 53645-95-7 2-bromo-5-phenyl-1,3,4-thiadiazole 
• 134-20-3 2-carbomethoxyaniline 
• 13373-11-0 2-chloro-5-phenyl-[1,3,4]thiadiazole 
• 116805-50-6 2-phenyl-6,7,8,9-tetrahydro-5H-1,3,4-thiadiazolo<2,3-b>quinazolin-5-one 
• 16951-33-0 3-amino-2,3-dihydro-2-thioxoquinazol-4(1H)-one 
• 65-85-0 benzoic acid 
• 2002-03-1 2-amino-5-phenyl-1,3,4-thiadiazole 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 16024-82-1 methyl 2-isothiocyanatobenzoate 
• 28873-29-2 3-benzoylamino-2-thioxo-2,3-dihydro-1H-quinazolin-4-one 

Downstream Products

• 71860-08-7 2-phenyl-[1,3,4]thiadiazolo[2,3-b]quinazoline-5-thione 
• 71860-01-0 2-(5-phenyl-[1,3,4]thiadiazol-2-ylamino)-benzoic acid 

Relevant academic research and scientific papers

Synthesis of 2-aryl-5H-[1,3,4]-thiadiazolo[2,3-b]quinazolin-5-ones

3-Amino-2-thioxo-1,2,3,4-tetrahydroquinazolin-4-ones were converted into 2-aryl-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-ones on treatment with carboxylic acids and POCl3. 3-Arylmethylidenamino-2-thioxo-1,2,3,4- tetrahydroquinazolin-4-ones also cyclized to 2-aryl-5H-[1,3,4]thiadiazolo[2,3-b] quinazolin-5-ones when oxidized with potassium chlorate in acetic acid, but on heating they were deaminated to give 2-thioxo-1,2,3,4-tetrahydroquinazolin-4-one and aryl nitriles. 2006 Springer Science+Business Media, Inc.

Condensed Heterocycles Containing the Pyrimidine Nucleus

Continuing earlier studies designed to obtain derivatives of 1,3,4-thiadiazolopyrimidin-5-one and of the isomeric 7-one of pharmacological interest, some novel compounds 2 and derivatives of 6,7,8,9-tetrahydro-5H-1,3,4-thiadiazoloquinazolin-