13373-11-0

Basic information

• Product Name: AIDS125547
• Synonyms: AIDS125547
• CAS NO: 13373-11-0
• Molecular Formula: C₈H₅ClN₂S
• Molecular Weight: 196.661
• Mol File: 13373-11-0.mol
• Article Data: 14

Chemical Properties

• Melting Point: 88 °C
• Boiling Point: 329.5°C at 760 mmHg
• Flash Point: 153.1°C
• Appearance: /
• Density: 1.379g/cm³
• Vapor Pressure: 0.00034mmHg at 25°C
• Refractive Index: 1.623
• PKA: -1.88±0.10(Predicted)
• CAS DataBase Reference: AIDS125547(CAS DataBase Reference)
• NIST Chemistry Reference: AIDS125547(13373-11-0)
• EPA Substance Registry System: AIDS125547(13373-11-0)

Safety Data

• Hazardous Substances Data: 13373-11-0(Hazardous Substances Data)

Usage

General Description

"AIDS125547" is a potent and selective inhibitor of the endosomal sorting complex required for transport (ESCRT) pathway, which is involved in the trafficking and degradation of proteins within the cell. It has been shown to specifically inhibit the activity of the VPS4 ATPase, a key component of the ESCRT machinery, leading to the disruption of endosomal protein sorting and the accumulation of intracellular vesicles. AIDS125547 has demonstrated promising anti-HIV activity by blocking the release of new virus particles from infected cells, as well as potential therapeutic effects in other diseases related to dysregulated protein trafficking and degradation. Further research is needed to fully understand the mechanisms of action and potential therapeutic applications of "AIDS125547."

InChI:InChI=1/C8H5ClN2S/c9-8-11-10-7(12-8)6-4-2-1-3-5-6/h1-5H

Upstream product

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Relevant articles and documents

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