2888-09-7

Usage

Uses

Used in Perfumery and Flavoring Industry:
Methyl 2-hydroxy-5-methoxy-3-nitrobenzoate 95+% is used as a key ingredient in the production of perfumes and flavoring agents due to its distinctive sweet, floral, and fruity scent. Its unique aroma profile contributes to the creation of various fragrance formulations, enhancing the sensory experience of consumers.
Used in Insect Repellent Industry:
Methyl 2-hydroxy-5-methoxy-3-nitrobenzoate 95+% is used as an active ingredient in insect repellents, providing effective protection against insects and other pests. Its natural repelling properties make it a preferred choice for eco-friendly and safe insect control solutions.
Used in Sunscreen Production:
In the cosmetics industry, Methyl 2-hydroxy-5-methoxy-3-nitrobenzoate 95+% is used in the formulation of sunscreens. Its ability to absorb ultraviolet radiation helps protect the skin from harmful UV rays, reducing the risk of sunburn and skin damage.
Used in Pharmaceutical Industry:
Methyl 2-hydroxy-5-methoxy-3-nitrobenzoate 95+% is utilized in the development and production of pharmaceuticals, particularly in the synthesis of various drug compounds. Its chemical properties make it a valuable intermediate in the manufacturing process, contributing to the efficacy and safety of medications.
Used in Food Industry:
Methyl 2-hydroxy-5-methoxy-3-nitrobenzoate 95+% is used as a flavoring agent in the food industry, particularly in the production of grape and orange flavors. Its ability to impart a natural and authentic taste to food products enhances the overall flavor profile, making it a popular choice for food manufacturers.

Upstream product

• 2905-82-0 methyl 5-methoxy-2-hydroxybenzoate 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 

Downstream Products

• 17894-27-8 methyl 2,5-Dimethoxy-3-nitrobenzoate 
• 1245534-28-4 2,2-dimethyl-1,3-dioxane-4,6-dione 
• 957110-20-2 5,8-dimethoxy-4-(2-nitrophenyl)-7-quinolinecarboxylic acid 
• 957110-22-4 7-[N-(2,2-dimethoxyethyl)-N-methyl]-carboxamide-5,8-dimethoxy-4-(2-nitrophenyl)quinoline 
• 55008-18-9 methyl 3-amino-2-hydroxy-5-methoxybenzoate 
• 2888-01-9 2-hydroxy-5-methoxy-3-nitrobenzoic acid 

Relevant academic research and scientific papers

An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: An ATP-competitive inhibitor of topoisomerase IIα and potent anticancer agent

Recently, we characterized neoamphimedine (neo) as an ATP-competitive inhibitor of the ATPase domain of human Topoisomerase IIα. Thus far, neo is the only pyridoacridine with this mechanism of action. One limiting factor in the development of neo as a the

Synthesis, structural investigations, hydrogen-deuterium exchange studies, and molecular modeling of conformationally stablilized aromatic oligoamides

Biasing the conformational preferences of aromatic oligoamides by internally placing intramolecular hydrogen bonds has led to a series of stably folded molecular strands. This article presents the results from extensive solid-state, solution, and computational studies on these folding oligomers. Depending on its backbone length, an oligoamide adopts a crescent or helical conformation. Surprisingly, despite the highly repetitive nature of the backbone, the internally placed, otherwise very similar intramolecular hydrogen bonds showed significantly different stabilities as demonstrated by hydrogen-deuterium exchange data. It was also observed that the hydrogen-bonding strength can be tuned by adjusting the substituents attached to the exterior of the aromatic backbones. Examining the amide hydrogen-deuterium exchange rates of trimers revealed that a six-membered hydrogen bond nearing the ester end is the weakest among all the four intramolecular hydrogen bonds of a molecule. This observation was verified by ab initio quantum mechanical calculations at the level of B3LYP/6-31G. Such a "weak point" creates the "battle of the bulge" where backbone twisting is centered, which is consistently observed in the solid-state structures of the four trimer molecules studied. In the solid state, the oligomers assemble into interesting one-dimensional structures. A pronounced columnar packing of short oligomers (i.e., dimers, trimers, and tetramer) and channel-like, potentially ion-conducting stacks of longer oligomers (i.e., tetramer, pentamer, and hexamer) were observed.

CETP INHIBITORS

Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. I