2901-92-0

Basic information

• Product Name: Benzenesulfinyl chloride, 4-chloro-
• CAS NO: 2901-92-0
• Molecular Formula: C6H4Cl2OS
• Molecular Weight: 195.069
• Mol File: 2901-92-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenesulfinyl chloride, 4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfinyl chloride, 4-chloro-(2901-92-0)
• EPA Substance Registry System: Benzenesulfinyl chloride, 4-chloro-(2901-92-0)

Safety Data

• Hazardous Substances Data: 2901-92-0(Hazardous Substances Data)

Upstream product

• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 106-54-7 p-Chlorothiophenol 
• 353243-81-9 4-chlorophenyl 2-(trimethylsilyl)ethyl sulfide 
• 108-90-7 chlorobenzene 
• 19378-58-6 N-(4-chloro-phenylsulfanylmethyl)-phthalimide 
• 143505-43-5 (2-((4- chlorophenyl)sulfinyl)ethyl)trimethylsilane 
• 100-03-8 4-chlorobenzenesulfinic acid 

Downstream Products

• 77198-05-1 C₁₉H₁₄Cl₂N₂OS 
• 110955-53-8 4-Chloro-N-isopropylidene-benzenesulfonamide 
• 79248-64-9 (S)-1,2:5,6-di-O-cyclohexylidene-α-D-glucofuranose p-chlorobenzenesulfinate 
• 79248-64-9 1,2:5,6-di-O-cyclohexylidene-α-D-glucofuranose p-chlorobenzenesulfinate 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 122053-99-0 (1R,4R)-2-[2-(4-Chloro-benzenesulfinyl)-pent-1-enylidene]-1,7,7-trimethyl-bicyclo[2.2.1]heptane 
• 122053-98-9 (1R,2R,4R)-2-<(4-Chlorophenyl)sulfinylethenylidene>-1,7,7-trimethylbicyclo<2.2.1>heptane 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 1146-44-7 4,4'-dichlorophenyl thiosulfonate 
• 154345-70-7 [(4-Chloro-benzenesulfinyl)-phenyl-methylene]-triphenyl-λ⁵-phosphane 
• 1027840-81-8 4-Chloro-benzenesulfinyl isocyanate 
• 21502-37-4 N-Triphenylphosphoranyliden-4-chlor-benzolsulfinsaeureamid 
• 708-66-7 p-chlorophenyl trifluoromethyl sulfoxide 
• 169216-73-3 4-(4-Chloro-benzenesulfinyl)-2,3,5,6-tetramethyl-phenol 

Relevant articles and documents

Direct conversion of sulfinamides to thiosulfonates without the use of additional redox agents under metal-free conditions

Direct conversion of sulfinamides to thiosulfonates is described. Without the use of additional redox agents, the reaction proceeds smoothly in the presence of TFA under metal-free conditions. This protocol possesses many advantages such as odourless and stable starting materials, broad substrate scope, selective synthesis, and mild reaction conditions. This journal is

Practical and highly stereoselective method for the preparation of several chiral arylsulfinamides and arylsulfinates based on the spontaneous crystallization of diastereomerically pure N-benzyl-N-(1-phenylethyl)- arylsulfinamides

A novel and simple process for the preparation of enantiomerically pure (SS)-benzenesulfinamide (SS)-3a, (SS)-p- toluenesulfinamide (SS)-3b, (SS)-p-chloro- benzenesulfinamide (SS)-3c and (SS)-p- fluorobenzenesulfinamide (SS)-3d has been developed. The treatment of arylsulfinyl chlorides with (R)-N-benzyl-1-phenylethanamine in the presence of excess triethylamine gave diastereomeric mixtures of N-benzyl-N-(1-phenylethyl)- arylsulfinamides 1, which underwent spontaneous crystallization to furnish diastereomerically pure (R,SS)-N-benzyl-N-(1-phenylethyl)- arylsulfinamides (R,SS)-1a-1d in 28%, 29%, 27% and 31% yields, respectively. The diastereomerically pure compounds (R,SS)-1 were then converted into four enantiopure (RS)-methyl arylsulfinates (RS)-2, and finally into four enantiopure (SS)- arylsulfinamides (SS)-3 in good yields.

Convenient method for the preparation of aryl sulfinyl chlorides

Reaction of activated arenes with thionyl chloride in the presence of montmorillonite K-10 clay affords the corresponding aryl sulfinyl chlorides in good yield.