29113-34-6

Basic information

• Product Name: 4-OXO-3,4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID
• Synonyms: 4-OXO-3,4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID;4-oxo-3,4-dihydroquinazoline-2-carboxylic acid(SALTDATA: 0.65H2O);Ethyl 4-Quinazolone-2-carboxylic Acid;4-Quinazolone-2-carboxylic Acid;4-keto-1H-quinazoline-2-carboxylic acid;4-oxo-1H-quinazoline-2-carboxylic acid;4-Oxo-1,4-dihydroquinazoline-2-carboxylic acid
• CAS NO: 29113-34-6
• Molecular Formula: C₉H₆N₂O₃
• Molecular Weight: 190.16
• Mol File: 29113-34-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: 215-216 °C (decomp)
• Boiling Point: 427.6°C at 760 mmHg
• Flash Point: 212.4°C
• Appearance: /
• Density: 1.56g/cm³
• Vapor Pressure: 4.5E-08mmHg at 25°C
• Refractive Index: 1.71
• PKA: 3.99±0.20(Predicted)
• CAS DataBase Reference: 4-OXO-3,4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-OXO-3,4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID(29113-34-6)
• EPA Substance Registry System: 4-OXO-3,4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID(29113-34-6)

Safety Data

• Hazardous Substances Data: 29113-34-6(Hazardous Substances Data)

Usage

General Description

4-OXO-3,4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID is a chemical compound that belongs to the class of quinazoline derivatives. It is an organic acid with a carboxylic acid group and a quinazoline ring structure. 4-OXO-3,4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID is commonly used in pharmaceutical research and drug development due to its potential medicinal properties. It has been studied for its potential as an antitumor agent and for its inhibitory effects on certain enzymes. Additionally, it has also been investigated for its potential role in treating cardiovascular diseases and neurological disorders. The chemical structure and properties of 4-OXO-3,4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID make it a promising candidate for further research and development in the field of medicinal chemistry.

InChI:InChI=1/C9H6N2O3/c12-8-5-3-1-2-4-6(5)10-7(11-8)9(13)14/h1-4H,(H,13,14)(H,10,11,12)

Upstream product

• 853029-98-8 4-oxo-3,4-dihydroquinazoline-2-carbonitrile 
• 105-36-2 ethyl bromoacetate 
• 28144-70-9 anthranilic acid amide 
• 1885-29-6 anthranilic acid nitrile 
• 861071-21-8 (2-cyano-phenyl)-oxalamic acid methyl ester 
• 29113-33-5 ethyl 4-oxo-3,4-dihydro-2-quinazolinecarboxylate 
• 61068-77-7 (2-cyano-phenyl)-oxalamic acid 
• 612-24-8 o-nitrobenzonitrile 

Downstream Products

• 491-36-1 4-Hydroxyquinazoline 
• 118372-87-5 4-oxo-N-phenyl-3,4-dihydroquinazoline-2-carboxamide 
• 947518-90-3 4-oxo-N-phenyl-3-(prop-2-yn-1-yl)-3,4-dihydroquinazoline-2-carboxamide 
• 948762-40-1 N-(3-methylphenyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide 

Relevant articles and documents

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Application of luotonin A derivatives in preparation of drugs for preventing or resisting plant diseases

The invention relates to natural pharmaceutical chemistry field and technical field of biopesticides and discloses application of any compound of luotonin A derivatives (Ia)-(Ii) in the preparation ofdrugs for preventing or resisting grape gray mold rot and rice blast. The compounds provided by the invention are derived from natural structure derivatives of a Chinese herbal medicine, namely peganum nigellastrum, have the characteristics of no pollution, safety and high efficiency, have the advantages of natural source pesticides, can be developed into plant source pesticides for producing environment-friendly and pollution-free agricultural products and belong to novel biopesticides.

Application of Luotonin A to prevention and treatment of aphid

The invention discloses application of a Luotonin A compound to prevention and treatment of green peach aphid, Chinese scholar tree aphid, hickory nut aphid and alfalfa aphid. The compound is high in aphid killing activity, can prevent and treat aphid harms and can serve as a new aphid-killing forerunner to be developed. Due to the fact that the compound is from a natural product of Chinese herbal medicine peganum nigellastrum bunge, the compound has the advantages of being free of pollution, safe and efficient, has the advantages of natural source pesticide and can serve as new potential forerunner molecules of plant source pesticide for producing green and pollution-free agricultural products.