29124-64-9

Basic information

• Product Name: N-(2-acetyl-4-bromophenyl)acetamide
• Synonyms: N-(2-acetyl-4-bromophenyl)acetamide
• CAS NO: 29124-64-9
• Molecular Formula: C₁₀H₁₀BrNO₂
• Molecular Weight: 256.1
• Mol File: 29124-64-9.mol
• Article Data: 13

Chemical Properties

• Melting Point: 158-159 °C
• Boiling Point: 420.1±40.0 °C(Predicted)
• Appearance: /
• Density: 1.504±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.68±0.70(Predicted)
• CAS DataBase Reference: N-(2-acetyl-4-bromophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-acetyl-4-bromophenyl)acetamide(29124-64-9)
• EPA Substance Registry System: N-(2-acetyl-4-bromophenyl)acetamide(29124-64-9)

Safety Data

• Hazardous Substances Data: 29124-64-9(Hazardous Substances Data)

Usage

General Description

N-(2-acetyl-4-bromophenyl)acetamide is a chemical compound with the molecular formula C10H10BrNO2. It is a derivative of acetanilide, containing an acetyl group and a bromine atom on the phenyl ring. N-(2-acetyl-4-bromophenyl)acetamide is commonly used in organic synthesis and pharmaceutical research, as it possesses anti-inflammatory and analgesic properties. It is also utilized as an intermediate in the production of various pharmaceuticals and organic compounds. The chemical properties of N-(2-acetyl-4-bromophenyl)acetamide make it a valuable resource in the development of new drugs and materials.

Upstream product

• 5234-26-4 N-(2-acetylphenyl)acetamide 
• 29124-56-9 1-(2-amino-5-bromophenyl)ethanone 
• 108-24-7 acetic anhydride 
• 4583-55-5 5-bromo-2,3-dimethyl-1H-indole 
• 551-93-9 2-aminoacetophenone 

Downstream Products

• 29124-56-9 1-(2-amino-5-bromophenyl)ethanone 
• 63362-11-8 1-(2-amino-5-bromo-phenyl)-ethanone; hydrochloride 
• 876-88-0 6-bromo-1H-cinnolin-4-one 
• 1225273-58-4 N-[2-acetyl-4-(4-methylpiperazin-1-yl)phenyl]acetamide 
• 65340-70-7 6-bromo-4-chloroquinoline 
• 201420-31-7 6-bromo-4-chloroquinoline-3-carbaldehyde 
• 2316-33-8 N-Acetyl-2-amino-5-brom-acetophenonoxim 
• 68211-13-2 4,6-dichlorocinnoline 
• 1366050-71-6 2-(4-(8-bromo-1H-imidazo[4,5-c]cinnolin-1-yl)phenyl)-2-methylpropanenitrile 
• 1366050-29-4 2-(4-(8-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1H-imidazo[4,5-c]cinnolin-1-yl)phenyl)-2-methylpropanenitrile 
• 1366050-70-5 2-(4-(3-amino-6-bromocinnolin-4-ylamino)phenyl)-2-methylpropanenitrile 
• 1366050-69-2 2-(4-(6-bromo-3-nitrocinnolin-4-ylamino)phenyl)-2-methylpropanenitrile 
• 876-88-0 6-bromocinnolin-4-ol 
• 68211-15-4 6-bromo-4-chlorocinnoline 

Relevant articles and documents

Auto-tandem PET and EnT photocatalysis by crude chlorophyll under visible light towards the oxidative functionalization of indoles

Chlorophyll is the most abundant photocatalytic pigment that enables plants to absorb solar energy and convert it to energy storage molecules. Herein, we report a tandem photocatalytic approach utilizing the natural pigment chlorophyll in crude form to achieve photoinduced electron transfer (PET) and energy transfer (EnT) towards the oxidative functionalization of indoles. Redox potentials, ESR, fluorescence quenching and UV experiments have evidenced the dual catalytic activity of chlorophyll. The highlight of the study is the auto-tandem photocatalytic role of chlorophyll to enable the green oxidation of indoles using molecular oxygen as the oxidant, water as the reaction medium, and photochemical energy from the visible region of the spectrum.

Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR

The identification and lead optimization of a series of pyridopyrimidinone derivatives are described as a novel class of efficacious dual PI3K/mTOR inhibitors, resulting in the discovery of 31. Compound 31 exhibited high enzyme activity against PI3K and mTOR, potent suppression of Akt and p70s6k phosphorylation in cell assays, and good pharmacokinetic profile. Furthermore, compound 31 demonstrated in vivo efficacy in a PC-3M tumor xenograft model.

Discovery of a novel series of thienopyrimidine as highly potent and selective PI3K inhibitors

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