29210-21-7

Basic information

• Product Name: 3-(hydroxymethyl)-2-phenyl-chromen-4-one
• Synonyms: 3-(hydroxymethyl)-2-phenyl-chromen-4-one
• CAS NO: 29210-21-7
• Molecular Formula: C₁₆H₁₂O₃
• Molecular Weight: 0
• Mol File: 29210-21-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 441.7°C at 760 mmHg
• Flash Point: 168.8°C
• Appearance: /
• Density: 1.288g/cm³
• Vapor Pressure: 1.4E-08mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: 3-(hydroxymethyl)-2-phenyl-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(hydroxymethyl)-2-phenyl-chromen-4-one(29210-21-7)
• EPA Substance Registry System: 3-(hydroxymethyl)-2-phenyl-chromen-4-one(29210-21-7)

Safety Data

• Hazardous Substances Data: 29210-21-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 14, p. 3083, 1973 DOI: 10.1016/S0040-4039(01)96325-7

InChI:InChI=1/C16H12O3/c17-10-13-15(18)12-8-4-5-9-14(12)19-16(13)11-6-2-1-3-7-11/h1-9,17H,10H2

Upstream product

• 50-00-0 formaldehyd 
• 1025-85-0 2,3-cis-3-Bromoflavanone 
• 98-88-4 benzoyl chloride 
• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 90-02-8 salicylaldehyde 
• 71972-66-2 3-methyl-2-phenyl-4H-1-benzopyran-4-one 
• 29220-20-0 3-acetoxymethyl-2-phenyl-4H-chromen-4-one 
• 118092-39-0 3-bromomethyl-2-phenyl-4H-chromen-4-one 
• 97139-84-9 2-benzoyloxypropiophenone 

Relevant articles and documents

SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF

The present invention belongs to the field of medicinal chemistry, and relates to substituted pyrimidine compounds as phosphatidylinositol 3-kinase (PI3K) δ inhibitor and a use thereof. In particular, the present invention provides a compound as shown by formula I or an isomer, pharmaceutically acceptable salt, solvate or prodrug thereof, the preparation methods of same and pharmaceutical compositions containing these compounds and a use of these compounds or compositions for treating cancer, hyperblastosis diseases or inflammatory diseases. The compounds of the present invention have a good inhibiting activity on PI3Kδ and have a high selectivity. It is hoped that these will be therapeutic agents for cancer, hyperblastosis diseases or inflammatory diseases.

HYDROXYMETHYLATION OF FLAVANONES

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