97139-84-9

Upstream product

• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 
• 98-88-4 benzoyl chloride 

Downstream Products

• 71972-66-2 3-methyl-2-phenyl-4H-1-benzopyran-4-one 
• 859439-78-4 3-methyl-2-phenyl-chromene-4-thione 
• 29220-20-0 3-acetoxymethyl-2-phenyl-4H-chromen-4-one 
• 118092-39-0 3-bromomethyl-2-phenyl-4H-chromen-4-one 
• 29210-21-7 3-(hydroxymethyl)-2-phenyl-4H-chromen-4-one 
• 102677-16-7 1-(2-hydroxy-phenyl)-2-methyl-3-phenyl-propane-1,3-dione 

Relevant academic research and scientific papers

SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF

The present invention belongs to the field of medicinal chemistry, and relates to substituted pyrimidine compounds as phosphatidylinositol 3-kinase (PI3K) δ inhibitor and a use thereof. In particular, the present invention provides a compound as shown by formula I or an isomer, pharmaceutically acceptable salt, solvate or prodrug thereof, the preparation methods of same and pharmaceutical compositions containing these compounds and a use of these compounds or compositions for treating cancer, hyperblastosis diseases or inflammatory diseases. The compounds of the present invention have a good inhibiting activity on PI3Kδ and have a high selectivity. It is hoped that these will be therapeutic agents for cancer, hyperblastosis diseases or inflammatory diseases.