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299411-67-9

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299411-67-9 Usage

General Description

Ethanone, 2-chloro-1-(4-chloro-2-fluorophenyl)- (9CI) is a chemical compound with the molecular formula C8H5Cl2FO. It is a ketone derivative with two chlorine atoms and one fluorine atom attached to a phenyl ring. Ethanone, 2-chloro-1-(4-chloro-2-fluorophenyl)- (9CI) is primarily used in research and development, as well as in the production of pharmaceuticals and agrochemicals. It may also have potential applications in the field of organic synthesis. However, there is limited information available about its specific properties and potential uses, and further research is needed to fully understand its potential benefits and risks.

Check Digit Verification of cas no

The CAS Registry Mumber 299411-67-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,9,4,1 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 299411-67:
(8*2)+(7*9)+(6*9)+(5*4)+(4*1)+(3*1)+(2*6)+(1*7)=179
179 % 10 = 9
So 299411-67-9 is a valid CAS Registry Number.

299411-67-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-1-(4-chloro-2-fluorophenyl)ethanone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:299411-67-9 SDS

299411-67-9Relevant articles and documents

IMIDAZO[1,2-B]PYRIDAZIN-6-AMINE DERIVATIVES AS KINASE JAK-2 INHIBITORS

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Page/Page column 16, (2014/02/16)

A compound represented by the general formula (I) wherein R1represents H or C1-C4 alkyl; R2 represents phenyl substituted with one or two substituents selected from the group consisting of halogen atom and OCsu

Development and a practical synthesis of the JAK2 inhibitor LY2784544

Mitchell, David,Cole, Kevin P.,Pollock, Patrick M.,Coppert, David M.,Burkholder, Timothy P.,Clayton, Joshua R.

experimental part, p. 70 - 81 (2012/05/31)

The route selection and process research and development of a practical synthesis for JAK2 inhibitor LY2784544 is described. The first-generation synthesis route, similar to that used in discovery for derivatization of a benzylic amine moiety, was 14 overall steps and possessed several steps that required extensive development for large-scale production. Route selection considerations led to a modified synthesis that utilized a novel vanadium-catalyzed carbon-carbon bond-forming arylation reaction for incorporation of the key benzylic morpholine moiety. A protecting group used to mask an amino pyrazole unit was modified from PMB to tert-butyl, resulting in a dramatic reduction in the overall length of the route. These two major changes resulted in an eight-step synthesis, which was six steps shorter than the first-generation synthesis. In the pilot plant, the new synthesis was scaled to produce >100 kg of LY2784544 in high yield and purity under GMP conditions. The overall development including the vanadium-catalyzed C-C bond-forming methodology, a ketone reductive deoxygenation, and a palladium-catalyzed amination is described.

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