29976-84-9

Upstream product

• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 94-30-4 ethyl 4-methoxybenzoate 
• 100-07-2 4-methoxy-benzoyl chloride 
• 100-09-4 4-methoxybenzoic acid 
• 794-94-5 p-Methoxybenzoic anhydride 
• 29976-81-6 2-anisoyloxy-5-methylacetophenone 

Downstream Products

• 83548-90-7 2-[4-Bromo-5-(4-methoxy-phenyl)-1-phenyl-1H-pyrazol-3-yl]-4-methyl-phenol 
• 136764-53-9 1a,7a-Dihydro-5-methyl-1a-(4-methoxyphenyl)-7H-oxireno<1>benzopyran-7-one 
• 6971-17-1 3-hydroxy-2-(4-methoxy-phenyl)-6-methyl-chromen-4-one 
• 115663-23-5 4'-methoxy-6-methylflavone oxime 
• 52752-69-9 2-bromo-1-(2-hydroxy-5-methyl-phenyl)-3-(4-methoxy-phenyl)-propane-1,3-dione 
• 35947-90-1 3-bromo-4'-methoxy-6-methylflavone 
• 75328-78-8 3-chloro-2-(4-methoxy-phenyl)-6-methyl-chromen-4-one 
• 141214-04-2 2-methyl-1-(2-methoxy-5-methylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione 
• 29976-77-0 6-methyl-4'-methoxyflavone 
• 29976-91-8 3-(2-hydroxy-5-methylphenyl)-5-(4-methoxyphenyl)isoxazole 
• 112753-49-8 3-(α-hydroxyamino-4-methylstyryl)-5-methylbenzisoxazole 
• 37689-62-6 2-[5-(4-methoxy-phenyl)-1-phenyl-1H-pyrazol-3-yl]-4-methyl-phenol 

Relevant academic research and scientific papers

Transition-Metal-Free Photoinduced Intramolecular Annulation of 2,3-Di(hetero)arylchromen-4-one

An efficient transition-metal-free photoinduced intracyclization of 4H-chromen-4-ones in EtOH-H2O (7:1, v/v) at ambient temperature for the construction of complicated fused-ring heteroaromatics is established. The reaction proceeds smoothly without requiring any catalysts/additives.

An efficient synthesis of 3-bromoflavones under solvent free conditions using grinding technique

Selective bromination of 1-(2-hydroxyphenyl)-3-phenylpropane- 1,3-diones has been carried out with ammonium bromide and ammonium persulphate at room temperature using grinding technique under solvent free conditions to give 2-bromo derivatives which on cyclodehydration with p-toluenesulphonic acid under grinding conditions give 3-bromoflavones. Also, flavones on bromination using above mentioned conditions give 3-bromoflavones directly.

One pot synthesis of 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones by modified Baker-Venkataraman transformation using microwave irradiation

Reaction of 2-hydroxyacetophenones with aromatic acid anhydrides in the presence of anhydrous barium hydroxide in dimethyl sulfoxide using microwave irradiation gives 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones directly in a single pot reaction in high yields.

Epoxidation of Flavones by Dimethyldioxirane

The synthesis of epoxides 2 by epoxidation of flavones 1 with isolated dimethyldioxirane (as acetone solution) at subambient temperatures is reported.These labile epoxides were isolated and completely characterized by UV, IR, 1H and 13C NMR, MS, and C,H analyses.Warming to room temperature led to rearrangement to afford quantitatively the 3-hydroxyflavones 3b,h,i,n.Treatment of the epoxides 2b,f with methanol led to the 3-hydroxy-2-methoxyflavanones 4b,f, as a mixture of cis and trans isomers.

Synthesis and Screening of Some 1,3-Propane Diones and Flavones

Variously substituted 1,3-propane diones and flavones are synthesized.Structures of the compounds are established by chemical and spectral data.The compounds are tested for antifungal and antibacterial activities.

Reaction of 3-Iodoflavanones with Hydrazine Hydrate & Phenylhydrazine: Synthesis of Pyrazoles

3-Iodoflavanones (IIa-d), obtained from 2'-hydroxy-4-methoxychalkones and ICl in acetic acid, when reacted with N2H4 * H2O in ethanol at room temperature give 3,5-diarylpyrazoles (IIIa-d) while with C6H5NH-NH2 * HCl in pyridine, 3,5-diaryl-1-phenylpyrazoles (IVa-d) are obtained.The identity of III and IV has been confirmed by independent and unambiguous synthesis of these pyrazoles from 2-hydroxydibenzoylmethanes.