29976-88-3

Upstream product

• 16635-13-5 2'-hydroxy-4-methoxy-5'-methylchalcone 
• 27770-80-5 2-(4-methoxyphenyl)-6-methylchroman-4-one 
• 81976-55-8 2,3-dihydro-2-(4-methoxyphenyl)-4H-6-methyl-benzopyran-4-one oxime 
• 1032-84-4 (E)-1-(2-hydroxy-5-methylphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 30036-28-3 3-(2-acetoxy-5-methyl-phenyl)-5-(4-methoxyphenyl)-Δ²-isoxazoline 

Relevant academic research and scientific papers

Synthesis of some new pyrimidines and isoxazolines and their pharmacological activity

The condensation of 5-methyl-2-hydroxy acetophenone 1 with different aromatic aldehydes in anhyd ethanol in presence of strong alkali gave 1-(5′-methyl-2′-hydroxy phenyl-1′-yl)-3-substituted arylidene-2-propen-1-ones (2a-d). Compounds (2a-d) underwent cyc

Synthesis of pyrazoline and isoxazoline in triethanolamine medium

Reactions of chalcones 1a-u with phenylhydrazine and hydrazine hydrate give pyrazolines 2a-u and with hydroxylamine hydrochloride yield isoxazolines 3a-c in triethanolamine medium. The structures of products are established by melting points, chemical studies and spectral data (IR and 1HNMR).

Reactions of a Chalcone with Hydroxylamine

2'-Hydroxy-4-methoxy-5'-methylchalcone (1) with hydroxylamine hydrochloride in dil.AcOH gives 3-(2-hydroxy-5-methylphenyl)-5-(4-methoxyphenyl)-Δ2-isoxazoline (2) instead of 2'-hydroxy-4-methoxy-5'-methylchalcone oxime (HMMCO, 3) as reported by

2,3-DIHYDRO-BENZO-γ-PYRONE OXIMES. PART VII A SIMPLE METHOD OF DIFFERENTIATION OF ISOMERIC DERIVATIVES OF Δ2-ISOXAZOLINE AND FLAVANONE OXIMES. A CORRECTION OF SOME STRUCTURES

The simple method of differentiation of isomeric derivatives i.e. (E)-2,3-dihydro-2-(4-ethoxyphenyl)-4H-benzopyran-4-one oxime (2) and corresponding Δ2-isoxazoline (3) on the basis of their UV and 1H NMR data, allows us to establish that the 2,