299912-59-7 Usage
General Description
Erlotinib Impurity 2 is a chemical compound commonly used as an intermediate or reference standard for research and development purposes. It is an impurity of the drug Erlotinib, which is primarily used to treat lung and pancreatic cancer. Erlotinib Impurity 2 is a potential metabolite of Erlotinib and is also known as (4-(3-Ethynylphenyl)-6,7-benzocoumarin. Its chemical structure includes a benzene ring and a coumarin moiety, and it may be used for the identification, characterization, and quantification of Erlotinib and its metabolites in pharmaceutical formulations and biological samples. Its availability and use are regulated by appropriate guidelines and regulations for proper handling, storage, and disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 299912-59-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,9,9,1 and 2 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 299912-59:
(8*2)+(7*9)+(6*9)+(5*9)+(4*1)+(3*2)+(2*5)+(1*9)=207
207 % 10 = 7
So 299912-59-7 is a valid CAS Registry Number.
299912-59-7Relevant articles and documents
New method for the preparation of erlotinib
-
, (2012/04/10)
The present invention refers to an alternative method for the preparation of Erlotinib through a new chemical reaction for the preparation of the 4-(3-aminophenyl)-2-methyl-3-butyn-2-ol key intermediate of formula (IV) according to the following scheme.