3010-04-6

Usage

InChI:InChI=1/C6H12N2/c1-2-3-5-8-6-4-7/h8H,2-3,5-6H2,1H3/p+1

Upstream product

• 50-00-0 formaldehyd 
• 143-33-9 sodium cyanide 
• 3858-78-4 n-butylamine hydrochloride 
• 74-90-8 hydrogen cyanide 
• 109-73-9 N-butylamine 
• 151-50-8 potassium cyanide 
• 107-16-4 glycolonitrile 
• 544-92-3 copper(I) cyanide 
• 123-72-8 butyraldehyde 
• 540-61-4 2-aminoacetonitrile 
• 107-14-2 chloroacetonitrile 

Downstream Products

• 19522-69-1 N-butylethylenediamine 
• 74875-50-6 N-Butyl-2-chloro-N-cyanomethyl-4-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-benzenesulfonamide 
• 137537-41-8 2-Benzoyl-N-butyl-N-cyanomethyl-benzamide 
• 58061-48-6 N-((pyridin-2-yl)methyl)butan-1-amine 
• 82560-32-5 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N-(N-butyl-N-cyanomethylaminosulfenyl)-N-methyl-carbamate 

Relevant academic research and scientific papers

Aminomethylation of lithiated nicotinamide: access to new pyridolactams

New 2,3-dihydropyrrolopyridinones were conveniently prepared by trapping lithiated pyridine carboxamides with highly reactive formimines. In this Letter, we report that a wide range of N-functionalised compounds can be synthesised in one step by this process, allowing the presence of ethers, acetals or ester moieties.

Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides

This invention relates to a novel solution phase process for the preparation of amide, carbamate, and sulfonamide combinatorial libraries. These libraries have utility for drug discovery and are used to form wellplate components of novel assay kits.

ELECTROCHEMICAL REDUCTIVE AMINATION. II. AMINATION OF ALIPHATIC ALDEHYDES WITH PRIMARY AMINES

The formation of a secondary amine by the electrolysis of an aqueous solution containing an aldehyde and a primary amine was studied.The formation of the secondary amines passes through the intermediate stage of an aldimine.The highest yield of secondary amine is attained at a molar ratio of primary amine to aldehyde of 1.2:1.As electrode material lead, cadmium, zinc, and copper may be used.As supporting electrolyte a phosphate buffer with a pH close to the pKa of the primary amine is recommended.By the method developed 32 amines with various structures were synthesized.

SYNTHESE D'IMINES LINEAIRES NON-STABILISEES PAR REACTIONS GAZ-SOLIDE SOUS VIDE(1).

Unstabilized imines are synthetized in gram-scale by vacuum dehydrochlorination of N-chloroalkylamines and by vacuum dehydrocyanation of α-aminonitriles on solid base.All the new compounds are characterized at low temperature by 1H, 13C NMR and IR spectroscopy.