30131-90-9

Upstream product

• 4346-94-5 thiosemicarbazide hydrochloride 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 64-19-7 acetic acid 
• 100-52-7 benzaldehyde 
• 79-19-6 thiosemicarbazide 
• 134-81-6 benzil 
• 30131-94-3 Δ⁶-5,6-diphenyl-5-methoxy-1,2,4-triazacyclohexene-3-thione 
• 37469-24-2 5,6-diphenyl-4H-[1,2,4] triazine-3-thione 

Downstream Products

• 56733-95-0 7-benzylidene-3,4-diphenyl-4H-thiazolo[2,3-c][1,2,4]triazin-6-one 
• 56734-04-4 3,4-diphenyl-7-(1-phenyl-ethyl)-4H-thiazolo[2,3-c][1,2,4]triazin-6-one 
• 56734-05-5 3,4-diphenyl-7-(1-phenyl-propyl)-4H-thiazolo[2,3-c][1,2,4]triazin-6-one 
• 56734-02-2 7-benzhydryl-3,4-diphenyl-4H-thiazolo[2,3-c][1,2,4]triazin-6-one 
• 56734-03-3 7-(4-methoxy-benzhydryl)-3,4-diphenyl-4H-thiazolo[2,3-c][1,2,4]triazin-6-one 
• 63586-75-4 3-methyl-6,7-diphenyl-7H-thiazolo[3,2-b][1,2,4]triazine 
• 63586-71-0 2,3-diphenyl-7,8-dihydro-3H,6H-[1,3]thiazino[3,2-b][1,2,4]triazine 
• 63586-74-3 3-(3-nitro-phenyl)-6,7-diphenyl-7H-thiazolo[3,2-b][1,2,4]triazine 
• 63586-68-5 3-(4-bromo-phenyl)-6,7-diphenyl-7H-thiazolo[3,2-b][1,2,4]triazine 
• 63586-69-6 3-(4-chloro-phenyl)-6,7-diphenyl-7H-thiazolo[3,2-b][1,2,4]triazine 
• 63586-72-1 6,7-diphenyl-3-p-tolyl-7H-thiazolo[3,2-b][1,2,4]triazine 
• 56223-63-3 6-Oxo-3,4-diphenylthiazolo<3,2-c>-1,2,4-triazin 
• 63586-67-4 6,7-diphenyl-7H-thiazolo[3,2-b][1,2,4]triazin-3-one 
• 56733-99-4 7-(4-dimethylamino-benzylidene)-3,4-diphenyl-4H-thiazolo[2,3-c][1,2,4]triazin-6-one 

Relevant academic research and scientific papers

Macrocyclization of cyclic thiosemicarbazones with mercury salts

A new cyclic Schiff base L1H3 derived from benzil and thiosemicarbazide has been prepared in the presence of NaBH4. Reactions of the new molecule and the cyclic 5-methoxy-5,6-diphenyl-4,5-dihydro-2H-[1,2,4]triazine-3-thione L2H2 with mercury chloride and nitrate are reported. Complexes of 1:2 stoichiometry are obtained from L1H3, but the reactions from L2H2 yield complexes of the macrocyclic Schiff base 5,6,11,12-tetraphenyl-1,2,4,7,8,10-hexaaza-cyclododeca-4,6,10,12-tetraene-3, 9-dithione L3H2, which indicates the macrocyclization of L2H2. A mechanism for the cyclization reaction based on the rupture of the C-N single bond in L2H2 is proposed. The electrochemical results of complex L3Hg makes it and its precursors, L2H2 and L3H2, outstanding candidates for mercury determination by appropriate electrode modification.

Efficient Green Synthesis and Computational Chemical Study of Some Interesting Heterocyclic Derivatives as Insecticidal Agents

A series of 5,5-diarylhydantoin (Dilantin) 3, 4, and 7, imidazole 1, 2, 5, 6, 8, and 9, thiazole 10–12, triazinthione 13, 15, 16, and 17, and thiadiazine 14 derivatives, containing diverse hydrophobic groups, were green synthesized through one-pot stepwise reaction of aromatic aldehydes, vitamin B1, and nitrogen nucleophiles, for example, urea, thiourea, and thiosemicarbazide using grinding technique as well as conventional thermal methods. Such synthesized compounds have potent insecticidal activities; for example, compounds 4, 6, and 17 exhibited the highest insecticidal activity against both Plutella xylostella and Helicoverpa armigera with minimum inhibitory concentration values at 500?μg/mL and LD50 activities at 50?μg/mL. The density functional theory was then applied to explore the structural and electronic characteristics of these compounds. All the synthesized compounds have been characterized based on their elemental analyses and spectral data.