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3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

301334-08-7

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301334-08-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 301334-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,1,3,3 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 301334-08:
(8*3)+(7*0)+(6*1)+(5*3)+(4*3)+(3*4)+(2*0)+(1*8)=77
77 % 10 = 7
So 301334-08-7 is a valid CAS Registry Number.

301334-08-7Downstream Products

301334-08-7Relevant academic research and scientific papers

Identification and initial SAR of silybin: An Hsp90 inhibitor

Zhao, Huiping,Brandt, Gary E.,Galam, Lakshmi,Matts, Robert L.,Blagg, Brian S.J.

, p. 2659 - 2664 (2011/06/22)

Through Hsp90-dependent firefly luciferase refolding and Hsp90-dependent heme-regulated eIF2α kinase (HRI) activation assays, silybin was identified as a novel Hsp90 inhibitor. Subsequently, a library of silybin analogues was designed, synthesized and evaluated. Initial SAR studies identified the essential, non-essential and detrimental functionalities on silybin that contribute to Hsp90 inhibition.

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