301537-10-0

Basic information

• Product Name: 2-(BROMOMETHYL)-1,3-DIMETHYL-5-(PHENYLMETHOXY)-BENZENE
• Synonyms: 2-(BROMOMETHYL)-1,3-DIMETHYL-5-(PHENYLMETHOXY)-BENZENE
• CAS NO: 301537-10-0
• Molecular Formula: C₁₆H₁₇BrO
• Molecular Weight: 305.21
• Mol File: 301537-10-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 405.7 °C at 760 mmHg
• Flash Point: 157.1 °C
• Appearance: /
• Density: 1.292 g/cm3
• Water Solubility: at 25 deg C (mg/L): 0.136
• CAS DataBase Reference: 2-(BROMOMETHYL)-1,3-DIMETHYL-5-(PHENYLMETHOXY)-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(BROMOMETHYL)-1,3-DIMETHYL-5-(PHENYLMETHOXY)-BENZENE(301537-10-0)
• EPA Substance Registry System: 2-(BROMOMETHYL)-1,3-DIMETHYL-5-(PHENYLMETHOXY)-BENZENE(301537-10-0)

Safety Data

• Hazardous Substances Data: 301537-10-0(Hazardous Substances Data)

Usage

General Description

2-(Bromomethyl)-1,3-dimethyl-5-(phenylmethoxy)-benzene is a chemical compound with the molecular formula C16H17BrO. It is a benzene derivative with a bromomethyl and phenylmethoxy substitution. 2-(BROMOMETHYL)-1,3-DIMETHYL-5-(PHENYLMETHOXY)-BENZENE is often used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is a colorless to pale yellow liquid at room temperature and is mainly used in research and development and industrial applications. Its properties and structure make it useful in organic synthesis and as a building block for more complex molecules.

Upstream product

• 70547-87-4 2,6-dimethyl-4-hydroxybenzaldehyde 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 95741-44-9 1-((4-bromo-3,5-dimethylphenoxy)methyl)benzene 
• 28924-92-7 4-(benzyloxy)-2,6-dimethylbenzaldehyde 
• 7463-51-6 4-bromo-3,5-dimethylphenol 
• 109467-96-1 2,6-dimethyl-4-benzyloxy-benzyl alcohol 

Downstream Products

• 955406-31-2 (R)-4-Benzyl-3-[(S)-2-(4-benzyloxy-2,6-dimethyl-benzyl)-pent-4-enoyl]-oxazolidin-2-one 
• 955406-35-6 trifluoro-methanesulfonic acid 3,5-dimethyl-4-[(R)-2-oxo-1-(2-trifluoromethanesulfonyl-4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-3-ylmethyl]-phenyl ester 
• 955406-32-3 (R)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-(4-benzyloxy-2,6-dimethyl-benzyl)-4-oxo-butyraldehyde 
• 955407-65-5 (R)-3-(4'-Fluoro-3,5-dimethyl-biphenyl-4-ylmethyl)-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955406-33-4 (R)-3-(4-Benzyloxy-2,6-dimethyl-benzyl)-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955406-34-5 (R)-3-(4-Hydroxy-2,6-dimethyl-benzyl)-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 

Relevant articles and documents

Unnatural chiral N - Tert -butanesulfinyl α-amino acid synthesis; A general synthetic strategy to N -boc-phenylalanine analogue alternatives

This work provides a general approach to unnatural chiral N-tert-butanesulfinyl α-amino acid synthesis with high yields and excellent diastereoselectivities (dr up to 98:2). The asymmetric addition of organometallic reagents to N-tert-butylsulfinyl imino acetate proceeded with excellent diastereo- and regioselectivities even on a 10 mmol scale. The sterically constrained 2,6-dimethyltyrosine (Dmt) derivative was also readily prepared from commercially available and inexpensive starting materials through simple steps.

CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1

The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compound