3019-18-9

Usage

Uses

Used in Pharmaceutical Industry:
2-(Ethylthio)-6-methylpyrimidin-4-ol is used as a potential active pharmaceutical ingredient for the development of antiviral and antifungal medications. Its unique structure and functional groups may contribute to its effectiveness in treating viral and fungal infections.
Used in Agricultural Industry:
2-(Ethylthio)-6-methylpyrimidin-4-ol may be used as a pesticide or herbicide in the agricultural industry. Its chemical properties could potentially offer effective control of pests and weeds, contributing to increased crop yields and protection against diseases.
Further research is required to fully understand the potential applications and effects of 2-(ethylthio)-6-methylpyrimidin-4-ol in various industries, ensuring its safe and effective use.

InChI:InChI=1/C7H10N2OS/c1-3-11-7-8-5(2)4-6(10)9-7/h4H,3H2,1-2H3,(H,8,9,10)

Upstream product

• 56-04-2 6-methyl-2-thiouracil 
• 75-03-6 ethyl iodide 
• 141-97-9 ethyl acetoacetate 
• 64-67-5 diethyl sulfate 
• 56-04-2 6-methyl-2-thiouracil 
• 74-96-4 ethyl bromide 
• 22874-42-6 4-hydroxy-2-mercapto-6-methylpyrimidine S-sodium salt 

Downstream Products

• 42487-69-4 6-methyl-2-piperidinopyrimidin-4(3H)-one 
• 19810-73-2 2-dimethylamino-6-methyl-3H-pyrimidin-4-one 
• 90831-56-4 N-acetyl-sulfanilic acid-(4-methyl-6-oxo-1,6-dihydro-pyrimidin-2-ylamide) 
• 37893-08-6 2-hydrazino-6-methylpyrimidin-4(3H)-one 
• 22727-18-0 4-chloro-2-ethylsulfanyl-6-methyl-pyrimidine 
• 626-48-2 6-Methyluracil 
• 590-88-5 1-methyltrimethylenediamine 
• 1002358-76-0 2-[(1-adamantyl)(phenyl)methyl]amino-6-methyl-4(3H)-pyrimidinone 
• 58010-88-1 benzaldehyde-(4-methyl-6-oxo-1,6-dihydro-pyrimidin-2-ylhydrazone) 
• 36951-92-5 2-Hydrazino-4-methoxy-6-methyl-pyrimidin 

Relevant academic research and scientific papers

Alkynylation of halo pyrimidines under Pd/C-copper catalysis: regioselective synthesis of 4- and 5-alkynylpyrimidines

5-Bromo-4-chloro-6-methylpyrimidines underwent facile Pd/C-Cu catalyzed coupling reactions with a variety of terminal alkynes, which resulted in the corresponding 4-alkynyl-5-bromopyrimidines, regioselectively, with good yields. 4-Chloro-5-iodo-6-methylpy

A green and facile synthesis of 6-Methyl-2-(alkylthio)pyrimidin-4(3H)-one

Reaction of 2-thiouracil (1) with alkylating agents, namely dimethyl sulphate, diethyl sulphate and benzyl chloride in the presence of potassium carbonate as a mild base, under green conditions, such as simple physical grinding of reactants or in solvents such as ethanol and PEG-600 and under microwave irradiation, gave, respectively 6-methyl-2-(methylthio)pyrimidin-4(3H) -one (2a, i.e., R=CH3), 6-methyl-2-(ethylthio) pyrimidin-4(3H)-one (2b, i.e., R = C2H5) and 6-methyl-2-(benzylthio)pyrimidin- 4(3H)-one (2c, i.e., R = PhCH2Cl). Alternately, condensation of ethyl acetoacetate with S-methylisothiouronium hemisulfate, S-ethylisothiouronium hemisulfate and S-benzyl isothiouronium chloride in ethanolic potassium hydroxide under reflux for 3 h gave 2a-c respectively.

Special features of the nucleophilic substitution of halogen in alkyl and benzyl halides with anions generated from 4-hydroxy-2-mercapto-6- methylpyrimidine

The nucleophilic substitution of halogen (chlorine, bromine, and iodine) in alkyl and benzyl halides has been effected in aqueous dioxane media with S-and O-anions generated from 4-hydroxy-2-mercapto-6-methylpyrimidine. Under these conditions replacement

Synthesis of 2-alkyl(aralkyl)sulfanyl-6-methylpyrimidin-4(3H)-ones and 4-alkyl(aralkyl)oxy-2-alkyl(aralkyl)sulfanyl-6-methylpyrimidines

2-Alkyl(aralkyl)sulfanyl-6-methylpyrimidin-4(3H)-ones and 4-alkyl(aralkyl)oxy-2-alkyl(aralkyl)-sulfanyl-6-methylpyrimidines having similar or different substituents on the sulfur and oxygen atoms were synthesized by alkylation of sodium salts derived from

STUDY OF REACTION OF THIOUREA WITH ETHYL 3-OXOBUTANOATE

Base-catalyzed formation of 6-methyl-2-thiouracil (III) by reaction of thiourea (I) with ethyl 3-oxobutanoate (II) involves N-(3-oxobutanoyl)thiourea (XI) as the reaction intermediate.In acid medium the compounds I and II do not react.In contrast to literature data, base-catalyzed cyclization of ethyl 3-thioureido-2-butenoate (IV) does not produce the compound III, but produces 2-amino-4-methyl-6-oxo-1,3-thiazine.