30406-61-2

Basic information

• Product Name: ethyl (4-chloro-3-methylphenoxy)acetate
• Synonyms: acetic acid, 2-(4-chloro-3-methylphenoxy)-, ethyl ester
• CAS NO: 30406-61-2
• Molecular Formula: C₁₁H₁₃ClO₃
• Molecular Weight: 228.6721
• Mol File: 30406-61-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 306.3°C at 760 mmHg
• Flash Point: 122°C
• Density: 1.174g/cm³
• Vapor Pressure: 0.000777mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: ethyl (4-chloro-3-methylphenoxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (4-chloro-3-methylphenoxy)acetate(30406-61-2)
• EPA Substance Registry System: ethyl (4-chloro-3-methylphenoxy)acetate(30406-61-2)

Safety Data

• Hazardous Substances Data: 30406-61-2(Hazardous Substances Data)

Upstream product

• 59-50-7 4-Chloro-3-methylphenol 
• 105-36-2 ethyl bromoacetate 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 72293-68-6 2-(4-chloro-3-methylphenoxy)acetohydrazide 
• 13359-34-7 <4-Chlor-3-methyl-phenoxy>-acetohydroxamsaeure 
• 120353-50-6 5-(4-chloro-3-methylphenoxy)methyl-3-(2,4-dichlorophenyl)aminomethyl-1,3,4-oxadiazole-2-thione 
• 72384-92-0 2-(3'-methyl-4'-chlorophenoxymethyl)-Δ²-1,3,4-oxadiazoline-5-thione 
• 72385-02-5 5-(4-chloro-3-methylphenoxy)methyl-3-(4-chlorophenyl)aminomethyl-1,3,4-oxadiazole-2-thione 
• 120353-49-3 5-(4-chloro-3-methylphenoxy)methyl-3-(2-chlorophenyl)aminomethyl-1,3,4-oxadiazole-2-thione 
• 120353-51-7 5-(4-chloro-3-methylphenoxy)methyl-3-(2-ethoxyphenyl)aminomethyl-1,3,4-oxadiazole-2-thione 
• 588-20-5 4-chloro-3-methylphenoxyacetic acid 
• 1263183-80-7 C₁₄H₁₂ClN₃O₂S 

Relevant articles and documents

Synthesis and biological evaluation of novel aryloxyacetic acid hydrazide derivatives as anticancer agents

In our continuing search for new anticancer agents, herein we report the synthesis of 2-(4-chloro-3-methylphenoxy)-N'-[(aryl)methylidene]acetohydrazides 3a–j and the evaluation of their anticancer activities on cell viability, morphological changes and ca

The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases

Neoplastic metastasis is a major process where tumor cells migrate from the primary tumor and colonize at other parts of our body to form secondary tumor. Cancer incidences are rising and novel anti-neoplastic compounds with new mechanism of actions are essential for preventing cancer related deaths. In the current examination, a novel series of pyridazine analogues 6a-l was synthesized and evaluated against metastatic neoplastic cells. Experimental data postulated compound 6j has potential cytotoxic efficacy with prolonged activity against various cancer cells, including A549, HepG2, A498, CaSki and SiHa cells. Moreover, compound 6j arrests the A549 migration and invasions markedly by counteracting matrix metalloproteinase (MMP)-2 and MMP-9 expressions. Also, compound 6j proved its potentiality against Dalton's solid lymphoma progression in-vivo by abridging MVD and MMP expressions. Compound 6j interacts with MMP-2 and MMP-9 by H- bond in-silico, thereby down regulates the MMPs action in tumourigenesis. Altogether, we concluded that compound 6j down regulates MMP-2 and MMP-9 and thereby impairs metastatic cancer cell migration and invasions which can be translated into a potent anti-neoplastic agent.

1,3,4-Thiadiazol-2-amine Derivatives as Urotensin-II Receptor (UT) Antagonists

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