30493-06-2

Basic information

• Product Name: 2-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde
• Synonyms: 2-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde
• CAS NO: 30493-06-2
• Molecular Weight: 256.691
• Mol File: 30493-06-2.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde(30493-06-2)
• EPA Substance Registry System: 2-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde(30493-06-2)

Safety Data

• Hazardous Substances Data: 30493-06-2(Hazardous Substances Data)

Usage

Chemical class

imidazo[1,2-a]pyridine derivatives

Type of compound

carbaldehyde

Contains

4-chlorophenyl group

Core structure

imidazo[1,2-a]pyridine

Potential applications

pharmaceutical industry (drug development, therapeutic agents)

Value in research

medicinal chemistry, drug discovery

Importance

investigation of potential uses and properties in various applications

Upstream product

• 504-29-0 2-aminopyridine 
• 38922-74-6 2-(4-chlorophenyl)imidazolo[1,2-a]pyridine 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 
• 1075-77-0 4-chlorocinnamaldehyde 
• 79-37-8 oxalyl dichloride 
• 5857-45-4 3-methylimidazo[1,2-α]pyridine 
• 99-91-2 para-chloroacetophenone 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 68-12-2 N,N-dimethyl-formamide 
• 104-88-1 4-chlorobenzaldehyde 
• 1314079-05-4 N-(1-(4-chlorophenyl)allyl)-2-aminopyridine 
• 59045-98-6 N-(4-chlorobenzylidene)pyridin-2-amine 
• 117459-95-7 N-(prop-2-yn-1-yl)pyridin-2-amine 
• 38427-94-0 N-(tert-butoxycarbonyl)-2-aminopyridine 

Downstream Products

• 1357622-10-6 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(4-methylsulfonylphenyl)prop-2-en-1-one 
• 1357622-22-0 6-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-4-[4(methylsulfonyl)phenyl]pyrimidin-2(1H)-one 
• 1357622-20-8 6-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-4-(4-chlorophenyl)pyrimidin-2(1H)-one 
• 1357622-07-1 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(4-chlorophenyl)prop-2-en-1-one 
• 1357622-14-0 6-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-4-phenylpyrimidin-2(1H)-one 
• 1357621-96-5 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-phenyl-prop-2-en-1-one 
• 1357622-15-1 6-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-4-(4-methylphenyl)pyrimidin-2(1H)-one 
• 1357621-97-6 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(4-methylphenyl)prop-2-en-1-one 
• 1357622-13-9 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(4-nitrophenyl)prop-2-en-1-one 
• 1357622-25-3 6-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-4-(4-nitrophenyl)pyrimidin-2(1H)-one 
• 1357622-21-9 6-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-4-(3-chlorophenyl)pyrimidin-2(1H)-one 
• 1357622-09-3 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(3-chlorophenyl)prop-2-en-1-one 
• 1357622-19-5 6-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-4-(2,4-dichlorophenyl)pyrimidin-2(1H)-one 
• 1357622-05-9 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(2,4-dichlorophenyl)prop-2-en-1-one 

Relevant articles and documents

One-pot multicomponent synthesis of novel substituted imidazo[1,2-a]pyridine incorporated thiazolyl coumarins and their antimicrobial activity

A series of novel substituted imidazo[1,2-a]pyridine incorporated thiazolyl coumarin derivatives (4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i, 4j, 4k, 4l, 4m, 4n, 4o, 4p, 4q, 4r, 4s, 4t) were synthesized in good yields via one-pot multicomponent condensation of su

Imidazopyridine linked triazoles as tubulin inhibitors, effectively triggering apoptosis in lung cancer cell line

A library of new imidazopyridine linked triazole hybrid conjugates (8a-r) were designed, synthesized and evaluated for their cytotoxicity against four cancer cell lines namely, human lung (A549), human prostate (DU-145), human colon (HCT-116) and breast (

Synthesis, Molecular Docking, BSA, and In Vitro Reactivation Study of Imidazopyridine Oximes Against Paraoxon Inhibited Acetylcholinesterase

Aim: To synthesize and evaluate the fused heterocyclic imidazo[1,2-a]pyridine based oxime as a reactivator against paraoxon inhibited acetylcholinesterase. Background: Organophosphorus compounds (OPs) include parathion, malathion, chlorpyrifos, monocrotop

Copper- A nd DMF-mediated switchable oxidative C-H cyanation and formylation of imidazo[1,2-: A] pyridines using ammonium iodide

The cyanation and formylation of imidazo[1,2-a]pyridines were developed under copper-mediated oxidative conditions using ammonium iodide and DMF as a nontoxic combined cyano-group source and DMF as a formylation reagent. Mechanistic studies indicate that the cyanation of imidazo[1,2-a]pyridines proceeds through a two-step sequence: Initial iodination and then cyanation. The cyanation has a broad substrate scope and high functional group tolerance, and can be safely conducted on a gram scale. A novel copper-mediated formylation using the widely available DMF as the formylation reagent and environmentally friendly molecular oxygen as the oxidant has also been developed. This protocol also provided a convenient approach for the synthesis of clinically used saripidem. This journal is

Novel method for one-step construction of substituted 2-phenylimidazo[1,2-a]pyridine-3-aldehyde by using DMF (N,N-dimethylformamide) as formylation reagent

The invention discloses a novel method for one-step construction of substituted 2-phenylimidazo[1,2-a]pyridine-3-aldehyde by using DMF (N,N-dimethylformamide) as a formylation reagent. According to the method, substituted 2-phenylimidazo[1,2-a]pyridine is