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(1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL, also known as mepyramine, is a first-generation antihistamine chemical compound that functions by blocking the effects of histamine, a substance responsible for causing allergic symptoms such as sneezing, itching, and watery eyes.
Used in Pharmaceutical Industry:
(1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL is used as an antihistamine medication for treating allergic reactions, such as hay fever, hives, and itching. It alleviates symptoms by inhibiting the histamine's effects, providing relief to individuals suffering from these conditions.
Used in Topical Preparations:
In the dermatological field, (1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL is used as an active ingredient in topical creams and ointments for the treatment of skin irritation and allergic rashes. Its application helps to soothe and reduce inflammation associated with these skin conditions.
Used in Oral Tablet Form:
(1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL is also available in oral tablet form, allowing for easy administration and absorption in treating allergic symptoms. This form is convenient for individuals seeking a non-topical method of relief.
Used in Topical Creams and Ointments:
As a component of topical creams and ointments, (1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL is used for its antihistamine properties to provide targeted relief for localized allergic reactions and skin irritations.

30517-60-3

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30517-60-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 30517-60-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,5,1 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 30517-60:
(7*3)+(6*0)+(5*5)+(4*1)+(3*7)+(2*6)+(1*0)=83
83 % 10 = 3
So 30517-60-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2O/c1-13-8-7-12-11(13)10(14)9-5-3-2-4-6-9/h2-8,10,14H,1H3

30517-60-3 Well-known Company Product Price

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  • Aldrich

  • (CBR01328)  (1-Methyl-1H-imidazol-2-yl)(phenyl)methanol  AldrichCPR

  • 30517-60-3

  • CBR01328-1G

  • 1,611.09CNY

  • Detail

30517-60-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (1-Methyl-1H-imidazol-2-yl)(phenyl)methanol

1.2 Other means of identification

Product number -
Other names (1-methylimidazol-2-yl)-phenylmethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

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More Details:30517-60-3 SDS

30517-60-3Relevant academic research and scientific papers

Isoprene-catalyzed lithiation of imidazole: Synthesis of 2-(hydroxyalkyl)- and 2-(aminoalkyl)imidazoles

Torregrosa, Rosario,Pastor, Isidro M.,Yus, Miguel

, p. 11148 - 11155 (2007/10/03)

2-Lithioimidazole was prepared by means of a new protocol, which consists of a slight excess of lithium metal in the presence of a substoichiometric amount of isoprene (20 mol%) in THF at room temperature. By reacting this organolithium with carbonyl elec

The synthesis of 2-substituted azoles through a one-pot three-component reaction

Deng, Yijun,Hlasta, Dennis J.

, p. 189 - 192 (2007/10/03)

We have discovered a new reaction whereby 2-substituted azoles are formed in the reaction of an azolium ylide with reactive carbonyl compounds. These products contain a leaving group in the α-position, which on solvolysis in the presence of nucleophiles yield azoles with a variety of α-substituents. We have developed new aspects of this chemistry and expanded the scope to include imidazoles, thiazoles, benzimidazoles and triazoles, such that in two reaction steps a wide diversity of substitution patterns are obtained.

Synthesis and reactivities of 1,3-dimethyl-2-(α-hydroxy-benzyl)imidazolium and 1,3-dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodides

Miyashita, Akira,Kurachi, Akihito,Matsuoka, Yoshiyuki,Tanabe, Noriko,Suzuki, Yumiko,Iwamoto, Ken-Ichi,Higashino, Takeo

, p. 417 - 426 (2007/10/03)

1,3-Dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodide (3a) was synthesized from 1-methylbenzimidazole (10) through two steps involving lithiation and quaternization. Treatment of 3a with 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (6) afforded 4-benzoyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (15a). 4-Benzoylquinazoline (14a) and 7-benzoyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (16a) were given by reaction of 3a with 4-chloroquinazoline (5) and 7-chloro-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (7). Treatment of 3a with benzaldehyde (9a) gave benzoin (8a). Similar results were obtained in the reactions of 1,3-dimethyl-2-(α-hydroxybenzyl)imidazolium iodide (4a).

Synthesis, Characterisation, and Reactivity of 1-(1-Methylimidazol-2-yl)ethenes

Abarca-Gonzalez, Belen,Jones, R. Alan,Medio-Simon, Mercedes,Quilez-Pardo, Juan,Sepulveda-Arques, Jose,Zaballos-Garcia, Elena

, p. 321 - 331 (2007/10/02)

Thermally labile 1-(1-methylimidazol-2-yl)ethenes, synthesised using the Wittig reaction, have been characterised as stable picrate or N-phenacyl salts.The free bases can be regenerated from the picrates on treatment with triethylamine and their reactivit

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