30517-60-3

Basic information

• Product Name: (1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL
• Synonyms: (1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL;CHEMBRDG-BB 4001285;1-METHYL-ALPHA-PHENYL-1H-IMIDAZOLE-2-METHANOL;(1-methyl-1H-imidazol-2-yl)(phenyl)methanol(SALTDATA: FREE)
• CAS NO: 30517-60-3
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.23
• Mol File: 30517-60-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 392.7°C at 760 mmHg
• Flash Point: 191.3°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 7.18E-07mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: (1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL(30517-60-3)
• EPA Substance Registry System: (1-METHYL-1H-IMIDAZOL-2-YL)-PHENYL-METHANOL(30517-60-3)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 30517-60-3(Hazardous Substances Data)

Usage

General Description

(1-Methyl-1H-imidazol-2-yl)-phenyl-methanol, also known as mepyramine, is a chemical compound that belongs to the class of first generation antihistamines. It works by blocking the effects of histamine, a substance in the body that causes allergic symptoms such as sneezing, itching, and watery eyes. Mepyramine is commonly used to relieve symptoms of allergic reactions, such as hay fever, hives, and itching. It can also be found in some topical creams and ointments for the treatment of skin irritation and allergic rashes. Mepyramine is available in various forms, including oral tablets and topical preparations, and is widely considered safe and effective when used as directed. However, like all medications, it may cause side effects in some individuals, such as drowsiness, dizziness, and dry mouth.

InChI:InChI=1/C11H12N2O/c1-13-8-7-12-11(13)10(14)9-5-3-2-4-6-9/h2-8,10,14H,1H3

Upstream product

• 380303-13-9 diisopropyl-carbamic acid (1-methyl-1H-imidazol-2-yl)-phenyl-methyl ester 
• 616-47-7 1-methyl-1H-imidazole 
• 100-52-7 benzaldehyde 
• 51081-36-8 2-lithium-N-methylimidazole 

Downstream Products

• 30148-17-5 (1-methyl-1H-imidazol-2-yl)(phenyl)methanone 
• 59563-84-7 phenyl-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-methanone 
• 55276-35-2 phenyl(quinazolin-4-yl)methanone 
• 129146-31-2 3-Methyl-1-(2-oxo-2-phenyl-ethyl)-2-(1-phenyl-vinyl)-3H-imidazol-1-ium; bromide 
• 127782-65-4 2-(1-phenyl-1-ethenyl)-1-methyl-1H-imidazole 

Relevant articles and documents

Isoprene-catalyzed lithiation of imidazole: Synthesis of 2-(hydroxyalkyl)- and 2-(aminoalkyl)imidazoles

2-Lithioimidazole was prepared by means of a new protocol, which consists of a slight excess of lithium metal in the presence of a substoichiometric amount of isoprene (20 mol%) in THF at room temperature. By reacting this organolithium with carbonyl elec

Synthesis and reactivities of 1,3-dimethyl-2-(α-hydroxy-benzyl)imidazolium and 1,3-dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodides

1,3-Dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodide (3a) was synthesized from 1-methylbenzimidazole (10) through two steps involving lithiation and quaternization. Treatment of 3a with 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (6) afforded 4-benzoyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (15a). 4-Benzoylquinazoline (14a) and 7-benzoyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (16a) were given by reaction of 3a with 4-chloroquinazoline (5) and 7-chloro-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (7). Treatment of 3a with benzaldehyde (9a) gave benzoin (8a). Similar results were obtained in the reactions of 1,3-dimethyl-2-(α-hydroxybenzyl)imidazolium iodide (4a).