306768-12-7

Basic information

• Product Name: N-Boc 4-Iodo-N-Methylaniline
• Synonyms: N-Boc 4-Iodo-N-Methylaniline
• CAS NO: 306768-12-7
• Molecular Formula: C₁₂H₁₆INO₂
• Molecular Weight: 333.16541
• Mol File: 306768-12-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Boc 4-Iodo-N-Methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc 4-Iodo-N-Methylaniline(306768-12-7)
• EPA Substance Registry System: N-Boc 4-Iodo-N-Methylaniline(306768-12-7)

Safety Data

• Hazardous Substances Data: 306768-12-7(Hazardous Substances Data)

Upstream product

• 159217-89-7 N-Boc-4-iodoaniline 
• 74-88-4 methyl iodide 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 28131-24-0 tert-butyl N-methyl-N-(phenyl)carbamate 
• 62404-59-5 4-(N-acetyl-N-methylamino)iodobenzene 
• 579-10-2 N-acetyl-N-methylaniline 
• 100-61-8 N-methylaniline 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 60577-34-6 p-iodo-N-methylaniline 
• 1422008-10-3 S-phenyl 4-((tert-butoxycarbonyl)(methyl)amino)benzothioate 
• 1301256-20-1 2-[4-(N-methyl-N-Boc-amino)phenyl]-6-(t-butyldimethylsilyloxy)benzo[b]thiophene 
• 916587-44-5 methyl-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pnenyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Novel quinoline-based fluorescent bioimaging probe, KSNP117, for sentinel lymph node mapping

Fluorescent imaging agents with biocompatibility and high sensitivity are urgently required for the accurate detection of sentinel lymph nodes (SLNs). Herein, we report the design of a novel quinoline-based fluorescent probe, designated KSNP117, which can be applied as a biomedical imaging agent in the sensitive and quantitative detection of SLNs. KSNP117 exerted no adverse effects on the proliferation of ovary and immune cells and also showed excellent serum stability with photo-brightening effects.In vivofluorescent imaging revealed the accumulation of KSNP117 in the SLNs of nude mice within 10 min post injection, withoutin vivotoxicity, which was consistent with the findings ofex vivoimaging. These results support the potential of KSNP117 as a promising lymphatic tracer for biomedical imaging applications.

Thermolysis and radiofluorination of diaryliodonium salts derived from anilines

Aniline-derived diaryliodonium salts were synthesized and functionalized in good to excellent yields by judicious utilization of electron-withdrawing protecting groups. This simple approach opens another route to radiolabeling amino arenes in relatively complex molecules, such as flutemetamol.