31036-66-5

Usage

General Description

2,5-Pyrrolidinedione, 1-(3-nitrophenyl)-, also known as 3-Nitrophenylpyrrolidinedione, is a chemical compound with the molecular formula C9H8N2O4. It is a yellow to brown crystalline powder that is used as a building block in the synthesis of pharmaceuticals and other organic compounds. This chemical is a versatile intermediate and has been studied for its potential applications in the field of drug discovery and development. It has also been used in the production of dyes, pigments, and other specialty chemicals. 3-Nitrophenylpyrrolidinedione is considered to be a potentially hazardous substance and should be handled with care, following proper safety precautions.

Upstream product

• 1797-93-9 3-(3-nitrophenylaminocarbonyl)propionic acid 
• 110-15-6 succinic acid 
• 99-09-2 3-nitro-aniline 
• 123-56-8 Succinimide 
• 13331-27-6 m-nitrobenzene boronic acid 
• 108-30-5 succinic acid anhydride 
• 7300-93-8 N-(3-nitro-phenyl)-maleimide 
• 42537-57-5 N-(3-nitrophenyl)maleamic acid 

Downstream Products

• 31036-67-6 N-m-Aminophenylsuccinimid 

Relevant academic research and scientific papers

Substituent chemical shifts of N-arylsuccinanilic acids, N-arylsuccinimides, N-arylmaleanilic acids, and N-arylmaleimides

NMR spectra of a series of N-arylsuccinanilic acids, N-arylsuccinimides, N-arylmaleanilic acids, and N-arylmaleimides were examined to estimate the electronic effect of the amide and imide groups on the chemical shifts of the hydrogen and carbon nuclei of the benzene ring.

Three isomeric N-(nitrophenyl)succinimides: Isolated molecules, hydrogen-bonded sheets and a hydrogen-bonded three-dimensional framework

Molecules of N-(2-nitrophenyl)succinimide, C10H 8N2O4 are linked into sheets by a combination of C-H...O and C-H...π(arene) hydrogen bonds. Molecules of N-(3-nitrophenyl)succinimide are linked into a three-dimen

First triphenylphosphine promoted reduction of maleimides to succinimides

Triphenylphosphine (TPP) in refluxing methanol effectively reduces maleimides 1a-g to the corresponding succinimides 2a-g in good yields. It was observed that some maleimides obtained from aromatic halogen compounds 1h-j were transformed into the corresponding succinamic acid methyl esters 3a-c by this reaction.

Cupric acetate mediated N-arylation by arylboronic acids: A preliminary investigation into the scope of application

A range of NH substrates of varying nucleophilicity were reacted with a selection of electronically diverse aryl boronic acids in the presence of cupric acetate in order to evaluate the generality of a previously described N-arylation procedure. The results of that investigation are discussed.