3111-89-5Relevant articles and documents
Synthesis, characterization, and biological evaluation of some novel pyrazolo[5,1-b]thiazole derivatives as potential antimicrobial and anticancer agents
Al-Aizari, Faiz A.,Almarhoon, Zainab M.,Alsayari, Abdulrhman,Asiri, Yahya I.,Ghabbour, Hazem A.,Kheder, Nabila A.,Mabkhot, Yahia N.,Muhsinah, Abdullatif Bin
, (2021/09/13)
The pharmacological activities of thiazole and pyrazole moieties as antimicrobial and anticancer agents have been thoroughly described in many literature reviews. In this study, a convenient synthesis of novel pyrazolo[5,1-b]thiazole-based heterocycles was carried out. The synthesized compounds were characterized by IR,1H and13C NMR spectroscopy and mass spectrometry. Some selected examples were screened and evaluated for their antimicrobial and anticancer activities and showed promising results. These products could serve as leading compounds in the future design of new drug molecules.
A comparative study of glycosyl thioimidates as building blocks for chemical glycosylation
Ranade, Sneha C.,Hasty, Scott J.,Demchenko, Alexei V.
, p. 360 - 379 (2013/10/08)
Our results indicate that the reactivity and the activation profile of thioimidate glycosyl donors vary significantly depending on the endocyclic heteroatom (N,O,S). Reactivity diminishes in accordance with the following sequence: O > S > N; and this tren
A one-pot conversion of di-substituted thiourea to O-organyl arylthiocarbamate using FeCl3
Sahoo, Santosh K.,Chakraborty, Supratim,Patel, Bhisma K.
experimental part, p. 143 - 153 (2012/06/01)
Unsymmetrical thiourea, which on demand can generate isothiocyanate in the presence of FeCl3, can serve as a latent isothiocyanate functionality and circumvent the difficulties associated with the direct use of reactive isothiocyanate functiona
