7442-11-7

Basic information

• Product Name: 1,1-diethyl-3-phenylthiourea
• CAS NO: 7442-11-7
• Molecular Formula: C₁₁H₁₆N₂S
• Molecular Weight: 208.3231
• Mol File: 7442-11-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 288°C at 760 mmHg
• Flash Point: 128°C
• Density: 1.113g/cm³
• Vapor Pressure: 0.00241mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: 1,1-diethyl-3-phenylthiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-diethyl-3-phenylthiourea(7442-11-7)
• EPA Substance Registry System: 1,1-diethyl-3-phenylthiourea(7442-11-7)

Safety Data

• Hazardous Substances Data: 7442-11-7(Hazardous Substances Data)

Usage

Abbreviation

DETU

Chemical classification

Thiourea derivative

Application

Accelerator in the vulcanization of rubber

Specific use

Production of tires

Function

Increases the rate of vulcanization

Impact on rubber properties

Improves mechanical properties such as tensile strength and elasticity

Health hazard

Causes skin and eye irritation

Long-term exposure risk

Potential harmful health effects

Safety measures

Proper handling and protective measures necessary when working with DETU

Upstream product

• 62-53-3 aniline 
• 103-72-0 phenyl isothiocyanate 
• 121-44-8 triethylamine 
• 75-15-0 carbon disulfide 
• 109-89-7 diethylamine 
• 102-08-9 N,N-diphenylthiourea 
• 16826-16-7 N,N-Diethyl-2-methyl-1-propen-1-amin 

Downstream Products

• 96311-35-2 -dithiocarbazinsaeure-methylester 
• 89418-88-2 1,1-diethyl-2-methyl-3-phenyl-isothiourea 
• 93866-94-5 -carbazinsaeure-ethylester 
• 3111-89-5 O-ethyl-N-phenylthiocarbamate 
• 149021-16-9 O-cyclohexyl N-phenylcarbamothioate 
• 17425-14-8 O-butyl N-phenylcarbamothioate 
• 24255-48-9 N,N-diethylbenzo[d]thiazol-2-amine 
• 1329430-11-6 1,1-diethyl-2,3-diphenyl-isothiourea 
• 1329430-09-2 N,N-diethyl-N'-phenyl-2-phenylsulfanyl-benzamidine 
• 78363-39-0 Cu[C₆H₅NC(S)N(C₂H₅)2]2 
• 790-04-5 3-phenyl-2-(phenylimino)-1,3-thiazolidin-4-one 
• 660-68-4 diethyl amine hydrochloride 
• 103-72-0 phenyl isothiocyanate 
• 74376-28-6 ethyl 5-methyl-2-phenylimino-1,3-oxathiole-4-carboxylate 

Relevant articles and documents

Photocatalytic synthesis of unsymmetrical thiourea derivativesviavisible-light irradiation using nitrogen-doped ZnO nanorods

An efficient, mild, and environmentally friendly route has been developed for the synthesis of unsymmetrical thiourea derivatives in moderate yields by the reaction of tertiary aromatic and aliphatic amines with phenyl-iso-thiocyanate in the presence of N-ZnO as a photocatalyst under visible-light irradiation. This method provides a pathway to activate the tertiary aromatic and aliphatic aminesviaC-N bond cleavage.

Actinide-Mediated Catalytic Addition of E-H Bonds (E=N, P, S) to Carbodiimides, Isocyanates, and Isothiocyanates

Unprecedented catalytic reactivity of actinide coordination complexes toward heterocumulenes, such as carbodiimides, isocyanates, and isothiocyanates is reported. The mono(imidazolin-2-iminato) thorium(IV) complex [Th(ImDippN){N(SiMe3)2}3] (1) was applied as a precatalyst for the addition of E-H (E=N, P, S) bonds to the Y≡C≡X core (Y=R2N; X=NR2, O, S) of carbodiimides, isocyanates, and isothiocyanates. The respective insertion products were obtained in high yields under mild reaction conditions, with complex 1 displaying high tolerance toward functional groups and heteroatoms. New reactivity: The mono(imidazolin-2-iminato) thorium complex [Th(ImDippN){N(SiMe3)2}3] was successfully applied as an active catalyst for the addition of E-H (E=N, P, S) bonds across the central Y≡N≡C≡X linkage of carbodiimides, isocyanates and isothiocyanates, yielding the respective insertion products in high yields and under mild reaction conditions.

Insertion of arynes into thioureas: A new amidine synthesis

Arynes, generated from trimethylsilyl phenyltriflate precursors, have been found to react with thioureas via a formal π-insertion into the C=S bond. The reaction contrasts with that of ureas, which proceeds via benzyne σ-insertion into the C-N bond, and r