31264-06-9

Upstream product

• 104-86-9 4-chlorobenzylamine 
• 104-88-1 4-chlorobenzaldehyde 
• 21913-13-3 N,N-bis(4-chlorobenzyl)amine 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 623-03-0 4-Cyanochlorobenzene 
• 100-46-9 benzylamine 
• 129041-31-2 N,N-bis(3-chlorobenzyl)amine 
• 7732-18-5 water 
• 945-51-7 1,1'-sulfinylbisbenzene 
• 124-38-9 carbon dioxide 
• 62-53-3 aniline 
• 253786-81-1 O-(1-naphthoyl)-N,N-bis(p-chlorobenzyl)hydroxylamine 
• 27032-10-6 4-chlorobenzyl azide 

Downstream Products

• 1063991-19-4 [PtCl₂(4-ClC₆H₄CH₂NH₂)(SOMe₂)] 
• 1095572-68-1 Pt(CH₃C₆H₄)(ClC₆H₃CHNCH₂(ClC₆H₄))S(C₂H₅)2 
• 619-56-7 4-chlorobenzamide 
• 104-88-1 4-chlorobenzaldehyde 
• 1019-85-8 2-(4-chlorophenyl)benzimidazole 
• 74-11-3 para-chlorobenzoic acid 

Relevant academic research and scientific papers

Transition-Metal-Controlled Inorganic Ligand-Supported Non-Precious Metal Catalysts for the Aerobic Oxidation of Amines to Imines

Most state-of-art transition-metal catalysts usually require organic ligands, which are essential for controlling the reactivity and selectivity of reactions catalyzed by transition metals. However, organic ligands often suffer from severe problems including cost, toxicity, air/moisture sensitivity, and being commercially unavailable. Herein, we show a simple, mild, and efficient aerobic oxidation procedure of amines using inorganic ligand-supported non-precious metal catalysts 1, (NH4)n[MMo6O18(OH)6] (M=Cu2+; Fe3+; Co3+; Ni2+; Zn2+, n=3 or 4), synthesized by a simple one-step method in water at 100 °C, demonstrating that the catalytic activity and selectivity can be significantly improved by changing the central metal atom. In the presence of these catalysts, the catalytic oxidation of primary and secondary amines, as well as the coupling of alcohols and amines, can smoothly proceed to afford various imines with O2 (1 atm) as the sole oxidant. In particular, the catalysts 1 have transition-metal ion core, and the planar arrangement of the six MoVI centers at their highest oxidation states around the central heterometal can greatly enhance the Lewis acidity of catalytically active sites, and also enable the electrons in the center to delocalize onto the six edge-sharing MO6 units, in the same way as ligands in traditional organometallic complexes. The versatility of this methodology maybe opens a path to catalytic oxidation through inorganic ligand-coordinated metal catalysis.

Molecular Structural Design of Conjugated Microporous Poly(Benzooxadiazole) Networks for Enhanced Photocatalytic Activity with Visible Light

A simple structural design principle and band position alignment of conjugated microporous polymers for enhanced photocatalytic efficiency is presented. The valence and conduction band positions of the polymer networks can be fine-tuned by altering the su

Nickel-decorated g-C3N4hollow spheres as an efficient photocatalyst for hydrogen evolution and oxidation of amines to imines

Photocatalysts composed of earth-abundant elements are highly desired for photocatalytic hydrogen evolution as well as oxidation of amines to imines without the requirement of precious metals. Herein, non-precious Ni metal decorated g-C3N4 hollow spheres

FeCl2-PPh3 as an efficient catalytic system for the acceptorless dehydrogenation of amines into imines

In this work, a novel and simple catalytic system including FeCl2, PPh3 and potassium tert-butoxide has been employed for the synthesis of imines from amines. In order to prove the catalytic acceptorless dehydrogenation pathway for this transformation, the liberated H2 gas is detected by NMR spectroscopy. By utilizing this protocol, a variety of arylamines were used successfully for the preparation of corresponding imines in good to excellent yields (on a 1?mmol scale, 73–91% yield for homocoupling, 71 and 91% for heterocoupling).

Heterojunctions between amorphous and crystalline niobium oxide with enhanced photoactivity for selective aerobic oxidation of benzylamine to imine under visible light

The formation of heterojunctions between two crystals with different band gap structures, acting as a tunnel for the unidirectional transfer of photogenerated charges, is an efficient strategy to enhance the photocatalytic performance of semiconductor pho

Unveiling the "three-Finger Pharmacophore" Required for p53-MDM2 Inhibition by Saturation-Transfer Difference (STD) NMR Initial Growth-Rates Approach

Inhibitors of the p53-MDM2 protein-protein interaction are emerging as a new and validated approach to treating cancer. Herein, we describe the synthesis and inhibitory evaluation of a series of isoquinolin-1-one analogues, and highlight the utility of an initial growth-rates saturation-transfer difference (STD) NMR approach supported by protein-ligand docking to investigate p53-MDM2 inhibition. The approach is illustrated by the study of compound 1, providing key insights into the binding mode of this kind of MDM2 ligands and, more importantly, readily unveiling the previously proposed three-finger pharmacophore requirement for p53-MDM2 inhibition. Molecular modelling: Inhibitors of the p53-MDM2 protein-protein interaction are emerging as a new and validated approach to treating cancer. Herein, the synthesis and inhibitory evaluation of a series of isoquinolin-1-one analogues is described, and the utility of an initial growth-rates STD NMR approach supported by protein-ligand docking to investigate p53-MDM2 inhibition is highlighted (see figure).

Metal-free oxidation of benzyl amines to imines

A convenient procedure for the oxidation of benzyl amines to the corresponding imines has been developed. Various imines were produced in good to excellent yields. Notably, no catalyst was needed, and H2O 2 was used as the oxidant an

ZnIn2S4: A photocatalyst for the selective aerobic oxidation of amines to imines under visible light

Flowerlike nanospheres of ZnIn2S4 consisting of interweaving nanoflakes were prepared by a rapid microwave-assisted solvothermal method. The photocatalytic performance of ZnIn2S4 in the aerobic oxidation of amines to imines is for the first time revealed. As-prepared ZnIn2S4 showed high efficiency for the transformations of various amines into their corresponding imines under visible-light irradiation by using air as the oxidant. The photocatalytic performance of ZnIn2S4 in the selective oxidation of amines to their corresponding imines is much higher than that of graphitic C3N4 and CdS previously reported. A plausible mechanism involving the oxygenation of amines to form aldehydes, followed by the nucleophilic addition of the amines to afford the final imines is proposed. The use of a cheap, environmentally friendly inorganic semiconductor photocatalyst and solar energy makes this transformation green and sustainable.

Calcined ZnCrCO3-HTlc for the oxidation of benzyl amines to Schiff bases

Oxidation of benzylamines to Schiff bases has been carried out using a mixed oxide catalyst obtained by the calcination of ZnCrCO3-HTlc which is a member of the anionic clay family.

The Combination of Charge and Energy Transfer Processes in MOFs for Efficient Photocatalytic Oxidative Coupling of Amines

Combining electron and energy transfer processes is very significant for efficient photocatalytic oxidation of organic molecules. The first synthesized MOF, Co2(L)(2,6-NDC)2·xguest (FJI-Y10, L = bis(N-pyridyl) tetrachloroperylene per