31332-88-4Relevant articles and documents
ETHYNYLBENZENE DERIVATIVES
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Page/Page column 45, (2012/03/26)
Disclosed are compounds of formulae (I), (II), and (II)I: and pharmaceutically acceptable salts thereof, wherein the variables, R, R1, R2, R3, R101, L, D, Q, Y, X, and Z are defined herein. These compounds are useful for treating Gram-negative bacteria infections.
Novel synthesis of [11C]GVG (Vigabatrin) for pharmacokinetic studies of addiction treatment
Ding, Y.-S.,Studenov, A. R.,Zhang, Z.,Gerasimov, M.,Schiffer, W.,Dewey, S. L.,Telang, F.
, p. S1008 - S1010 (2007/10/03)
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New synthetic routes to α-amino acids and γ-oxygenated α-amino acids. Reductive denitration and oxidative transformations of γ-nitro-α-amino acids
Crossley, Maxwell J.,Fung, Yik M.,Kyriakopoulos, Efstathia,Potter, Jeffrey J.
, p. 1123 - 1130 (2007/10/03)
Transformation of γ-nitro-α-amino acid derivatives into α-amino acids by reductive denitration, into the γ-oxo-α-amino acids by ozonolysis of the corresponding amino acid ester nitronate derivatives, and into γ-hydroxy-α-amino acid derivatives by subsequent reduction of the oxo functionality, can be achieved in good yields. As the γ-nitro-α-amino acid derivatives are prepared from N,O-protected dehydroalanines derivable from the corresponding alanine, serine and cysteine derivatives by specific routes, the overall procedures provide a means for selective conversion of these simple α-amino acids into more complex ones.
