3140-01-0Relevant articles and documents
A scalable and green one-minute synthesis of substituted phenols
Elumalai, Vijayaragavan,Hansen, J?rn H.
, p. 40582 - 40587 (2020/11/18)
A mild, green and highly efficient protocol was developed for the synthesis of substituted phenols via ipso-hydroxylation of arylboronic acids in ethanol. The method utilizes the combination of aqueous hydrogen peroxide as the oxidant and H2O2/HBr as the reagent under unprecedentedly simple and convenient conditions. A wide range of arylboronic acids were smoothly transformed into substituted phenols in very good to excellent yields without chromatographic purification. The reaction is scalable up to at least 5 grams at room temperature with one-minute reaction time and can be combined in a one-pot sequence with bromination and Pd-catalyzed cross-coupling to generate more diverse, highly substituted phenols.
Benzimidazole-based palladium-N-heterocyclic carbene: A useful catalyst for C-C cross-coupling reaction at ambient condition
Gupta, Sumanta,Basu, Basudeb,Das, Sajal
, p. 122 - 128 (2013/01/15)
A convenient way for the synthesis of benzimidazole-based Pd-N-heterocyclic carbene complex and its structural characterization are described. The complex efficiently catalyzes Suzuki cross-coupling reaction in a wide variety of substrates including heteroaromatic system at ambient condition. The catalyst is also effective for multi Suzuki cross-coupling reaction. In addition, the catalyst is equally active toward C-C cross-coupling reaction between acid chloride and arylboronic acid, giving the desired ketones in high yield.
Tandem reactions of cis-2-acyl-1-alkynyl-1-aryl cyclopropanes tuned by gold(i) and silver(i) catalysts: Efficient synthesis of pyran-fused indene cores and 2,4,6-trisubstituted phenols
Zhang, Xiao-Ming,Tu, Yong-Qiang,Jiang, Yi-Jun,Zhang, Yong-Qiang,Fan, Chun-An,Zhang, Fu-Min
supporting information; experimental part, p. 4726 - 4728 (2010/01/16)
Tandem reactions of cis-2-acyl-1-alkynyl-1-aryl cyclopropanes 1 tuned by gold(i) and silver(i) catalysts are described, which afford selectively the key pyran-fused indene cores 2 and the 2,4,6-trisubstituted phenols 3 in good yields, respectively. The Ro