317318-65-3

Basic information

• Product Name: Acetic acid, [4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy ]-, methyl ester
• CAS NO: 317318-65-3
• Molecular Formula: C21H18F3NO3S2
• Molecular Weight: 453.506
• Mol File: 317318-65-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetic acid, [4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy ]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy ]-, methyl ester(317318-65-3)
• EPA Substance Registry System: Acetic acid, [4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy ]-, methyl ester(317318-65-3)

Safety Data

• Hazardous Substances Data: 317318-65-3(Hazardous Substances Data)

Upstream product

• 317318-96-0 [4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-methanol 
• 86487-19-6 tributyl(4-(trifluoromethyl)phenyl)stannane 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 637-89-8 4-sulfanylphenol 
• 15015-57-3 bis(4-hydroxyphenyl)disulfide 
• 873066-26-3 [4-bromo-2-(4-trifluoromethylphenyl)thiazol-5-yl]methanol 
• 873066-23-0 4-trifluoromethylphenylboronic dimethyl ester 
• 1706-60-1 (4-Mercapto-phenoxy)-acetic Acid Methyl Ester 
• 317318-97-1 5-(chloromethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole 
• 167012-47-7 methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate 

Relevant articles and documents

Synthesis of the PPARβ/δ-selective agonist GW501516 and C4-thiazole-substituted analogs

Sequential, position-selective, Pd-catalyzed cross-coupling reactions of 2,4-dibromo-5-hydroxymethylthiazole provided the scaffold for the synthesis of GW501516, the most potent PPARβ/δ agonist yet described, and equally selective analogs at the thiazole-

Activator of PPAR delta

Compounds of Formula (I) are disclosed. These compounds include selective activators of human PPAR delta.