873066-26-3Relevant articles and documents
Synthesis of the PPARβ/δ-selective agonist GW501516 and C4-thiazole-substituted analogs
Pereira, Raquel,Gaudon, Claudine,Iglesias, Beatriz,Germain, Pierre,Gronemeyer, Hinrich,De Lera, Angel R.
, p. 49 - 54 (2007/10/03)
Sequential, position-selective, Pd-catalyzed cross-coupling reactions of 2,4-dibromo-5-hydroxymethylthiazole provided the scaffold for the synthesis of GW501516, the most potent PPARβ/δ agonist yet described, and equally selective analogs at the thiazole-