319-87-9

Usage

Uses

1-Fluoropentachlorobenzene is used as an intermediate in the chemical synthesis industry for the production of various chemical compounds. Its application is primarily in the synthesis of other compounds, making it a crucial component in the development of new chemicals with specific properties and applications. However, due to its potential environmental and health risks, strict regulations and controls are in place to minimize its release and exposure.

InChI:InChI=1/C6Cl5F/c7-1-2(8)4(10)6(12)5(11)3(1)9

Upstream product

• 462-06-6 fluorobenzene 
• 1780-40-1 2,4,5,6-tetrachloropyrimidine 
• 598-88-9 1,2-dichloro-1,2-difluoroethene 
• 118-74-1 hexachlorobenzene 
• 827-05-4 Pentabromofluorobenzene 
• 445-29-4 o-fluoro-benzoic acid 
• 7782-50-5 chlorine 
• 79-38-9 Chlorotrifluoroethylene 
• 781-15-7 1,2,3,4-tetrachloro-5,6-dinitrobenzene 
• 82-68-8 Quintozene 

Downstream Products

• 90986-01-9 3-(2,3,4,5,6-Pentachlorophenoxy)-anisole 
• 90985-97-0 4-(2,3,4,5,6-Pentachlorophenoxy)-anisole 
• 1825-21-4 Pentachloroanisole 
• 133-49-3 pentachlorothiophenol 
• 319-88-0 1,3,5-trichlorotrifluorobenzene 
• 78576-71-3 3-(2,3,4,5,6-Pentachlorophenoxy)-phenole 
• 78576-70-2 4,5-Dichloro-2-(2,3,4,5,6-pentachlorophenoxy)-phenol 
• 78576-72-4 4-(2,3,4,5,6-Pentachlorophenoxy)-phenol 

Relevant academic research and scientific papers

Polyhalogenonitrobenzenes and derived compounds part 4. Attempted fluorination of 1,2,3,4-tetrachloro-5,6-dinitrobenzene

Attempted fluorination of 1,2,3,4-tetrachloro-5,6-dinitrobenzene with potassium fluoride to give 1,2,3,4-tetrafluoro-5,6-dinitrobenzene in DMF or sulpholane, or under solid/liquid phase transfer conditions in toluene using Aliquat 336, TBAI or 18-Crown-6 failed to yield any products resulting from displacement of Cl by F. Rather surprisingly, the two products obtained were pentachloronitrobenzene and pentachlorofluorobenzene.

LES FLUORATIONS COMPAREES DES CHLOROPYRIMIDINES ET DE LA CHLORO-S-TRIAZINE

The fluorinations of tetrachloropyrimidine, 2,4,6-trichloropyrimidine and trichloro-s-triazine were carried out in sealed tubes with KF in presence of inert gas and then compared.The fluorinated derivatives C4FxClyN2 with x + y = 4, O - were investigated and compared; the molar yields were found to be always higher than 50percent in our experimental conditions.We compare with the fluorinations of 2,4 and 4,6-dichloropyrimidine.It is possible to obtain directlyin good proportions, such fluorinated derivatives as 5-chlorotrifluoropyrimidine, trifluoropyrimidine and others.At high temperature (4OO deg C for 16h), tetrachloropyrimidine, in presence of KF, gave products of pyrolysis and condensation such as the fluorinated derivatives of C6Cl6 and C5Cl5N: C6FCl5, C6F2Cl4... or C5FCl4N, C5F2Cl3N...

LA FLUORATION DE L'HEXACHLOROBENZENE ET DE LA PENTACHLOROPYRIDINE EN MILIEU DE FLUORURE DE POTASSIUM SOLIDE

The fluorinations of hexachlorobenzene and pentachloropyridine were carried out in sealed tubes with KF in presence of inert gas; the fluorinated derivatives C6FxCly x + y = 6 0 - are investigated and compared; the molar yield varied from 45percent to 90percent.It is possible to get directly and selectively some fluorinated drivatives as C5Cl2F3N.The fluorinations in liquid KF-KCl and solid KF are compared.

METHOD FOR THE PRODUCTION OF 1,3,5-TRIFLUORO-2,4,6-TRICHLOROBENZENE FROM FLUOROBENZENE DERIVATIVES

Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene, comprising steps A) and B): A) chlorination of fluorobenzene derivatives of formula (II), in which X = fluorine or H, Z = nitro, bromo or chloro and n = 0 or 1-4 and B) fluorination of the distillation residue and separation by distillation of the 1,3,5-trifluoro-2,4,6-trichlorobenzene thus produced.

Preparation process of fluorine substituted aromatic compound

A preparation process of a fluorine substituted aromatic compound comprising reacting an alkali metal or alkali earth metal salt of an aromatic compound having a hydroxy group with an organic fluorinating agent is disclosed. As a representative fluorinating agent, a bis-dialkylamino-difluoromethane compound, for example, 2,2′-difluoro-1,3-dimethylimidazolidine, is exemplified. According to the process, an industrially useful fluorinated aromatic compound, for example, a fluorobenzene, a fluorine substituted benzophenone, a fluorine substituted diarylsulfone can be prepared with ease in economy without specific equipment.