32102-77-5

Upstream product

• 4885-14-7 3-benzoyldurene 
• 700-12-9 pentamethylbenzene, 
• 71-43-2 benzene 
• 64-17-5 ethanol 
• 95-93-2 1,2,4,5-tetramethylbenzene 
• 100-51-6 benzyl alcohol 
• 98-88-4 benzoyl chloride 
• 538-86-3 benzyl methyl ether 
• 3012-37-1 benzyl thiocyanate 
• 100-44-7 benzyl chloride 

Downstream Products

• 56428-00-3 bis(4-chlorobenzyl) ether 
• 855288-26-5 4-benzyl-2,3,5,6-tetramethyl-benzophenone 

Relevant academic research and scientific papers

Iron-catalyzed benzylation reaction of arenes with benzyl thiocyanates

A novel, regioselective protocol for the synthesis of diphenylmethane derivatives has been developed by using iron-catalyzed Friedel-Crafts reaction of arenes with benzyl thiocyanates. In the presence of FeBr3, a variety of benzyl thiocyanates underwent the reaction with arenes to selectively afford the corresponding diarylmethane derivatives in moderate to high yields. Georg Thieme Verlag Stuttgart · New York.

Iron-containing defect-rich mixed metal oxides for Friedel-Crafts alkylation

Several stable iron-containing spinel oxides with the composition CuFe 2O4 or FeCr2O4 were prepared by different methods including thermal nitrate decomposition, combustion synthesis, and mechano-chemical synthesis. Materials were compared to commercially available spinels produced by conventional ceramic route with respect to their structural properties and catalytic activity. Phase compositions and microstructures of the catalysts were studied in detail. The catalysts were tested in the Friedel-Crafts alkylation of various aromatic compounds with different alkyl halides as alkylating agents. Microstructural properties (microstrains) of the synthesized binary oxides have been identified as a reason for the increased reactivity. Even at low reaction temperatures of 50-70 °C catalysts maintained their high activity resulting in TOFs of up to 3000 h -1 and excellent selectivity with total heterogeneous behavior in catalysis.

Benzylation of arenes through FeCl3-catalyzed Friedel-Crafts reaction via C-O activation of benzyl ether

Various benzyl ethers were converted to benzyl arenes via a FeCl3-catalyzed Friedel-Crafts alkylation reaction under mild condition in good yields. This method also offered a simple and practical approach to synthesize di- or tri-aryl methanes and aryl heteroaryl methanes through the activation of C-O bonds.

An efficient synthesis of unsymmetrical diarylmethanes from the dehydration of arenes with benzyl alcohols using InCl3·4H2O/acetylacetone catalyst system

An efficient and practical synthesis of unsymmetrical diarylmethanes has been achieved from the dehydration of arenes with benzyl alcohols in the presence of catalytic amount of InCl3·4H2O/acetylacetone.