3217-09-2

Usage

Uses

Used in Pharmaceutical Industry:
1-Propanol, 2-[(phenylmethyl)amino]is used as a solvent and intermediate for the synthesis of pharmaceuticals, contributing to the development of new drugs and medicines. Its versatility in chemical reactions makes it a valuable component in the production process.
Used in Pesticide Industry:
In the pesticide industry, 1-Propanol, 2-[(phenylmethyl)amino]is utilized as a solvent and intermediate in the formulation of various pesticides. Its properties allow for the creation of effective and targeted pest control solutions.
Used in Organic Compounds Synthesis:
1-Propanol, 2-[(phenylmethyl)amino]is used as a solvent and intermediate in the synthesis of other organic compounds, playing a crucial role in the chemical industry for the production of a wide range of products. Its reactivity and solubility properties make it a preferred choice for many chemical processes.

Upstream product

• 6168-72-5 2-Amino-1-propanol 
• 100-52-7 benzaldehyde 
• 1252059-62-3 C₁₂H₁₅NO₂ 
• 100-39-0 benzyl bromide 
• 2198-64-3 N-Benzoylalanine 

Downstream Products

• 911792-37-5 4-benzyl-5-methylmorpholin-2-one 
• 1420476-95-4 2-benzyl-3-methyl-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione 
• 1420476-86-3 2-benzyl-7-bromo-3-methyl-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione 
• 1401233-83-7 ethyl 4-benzyl-5-methylmorpholine-2-carboxylate 
• 1401233-84-8 4-benzyl-5-methylmorpholine-2-carboxylic acid 
• 119128-21-1 4-benzyl-5-methylmorpholin-3-one 
• 120800-93-3 2-[Benzyl-(2-hydroxy-1-methyl-ethyl)-amino]-N-(1-phenyl-ethyl)-acetamide 
• 349659-85-4 N-benzyl-N-[(1S)-2-hydroxyimino-1-methylethyl]-(E)-2-phenyleth-1-ene-1-sulfonamide 
• 349659-73-0 N-benzyl-N-[(1S)-1-methyl-2-oxoethyl]-(E)-2-phenyleth-1-ene-1-sulfonamide 
• 349659-61-6 N-benzyl-N-[(1S)-2-hydroxy-1-methylethyl]-(E)-2-phenyleth-1-ene-1-sulfonamide 

Relevant academic research and scientific papers

Anchored Palladium Complex-Generated Clusters on Zirconia: Efficiency in Reductive N-Alkylation of Amines with Carbonyl Compounds under Hydrogen Atmosphere

Carbon-nitrogen bond formation is an important method on both laboratory and industrial scales because it realizes the production of valuable pharmaceuticals, agrochemicals, and fine chemicals. Direct reductive N-alkylation of amines with carbonyl compounds via intermediary imine compounds, especially under catalytic hydrogenation conditions, is one of the most convenient, economical, and environmentally friendly methods for this process. Here we report a novel palladium species on zirconia having specific activity towards hydrogenation of imines but other carbonyl groups remaining intact. The present catalytic property offers a practical synthetic method of functionalized secondary amines by reductive N-alkylation under mild conditions with high atom-efficiency. Mechanistic studies revealed that the catalytically active species is the palladium cluster, which is generated in situ from molecular palladium complexes on the support by exposure to atmospheric hydrogen. These fundamental findings are expected to progress in developing novel cluster catalysts for chemical processes directed towards a sustainable society.

6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE AND 6,7-DIHYDRO-4H-TRIAZOLO[1,5-A]PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES

The present invention relates to compounds of the formula (I), or pharmaceutically acceptable salts, enantiomer or diastereomer thereof, wherein R1 to R4 and Q are as described above. The compounds may be useful for the treatment or prophylaxis of hepatitis B virus infection.

A COMPOUND FOR INHIBITING HUMAN 11-β-HYDROXY STEROID DEHYDROGENASE TYPE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention relates to a novel compound, or a stereoisomer, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for human-11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) comprising the same. The invention provides a compound, which has excellent activity and solubility and is more efficiently formulated and delivered, and a pharmaceutical composition for human-11-beta-hydroxysteroid dehydrogenase type 1 comprising the same.

Microwave-assisted regioselective ring opening of non-activated aziridines by lithium aluminium hydride

A new synthetic protocol for the LiAlH4-promoted reduction of non-activated aziridines under microwave conditions was developed. Thus, ring opening of 2-(acetoxymethyl)aziridines provided the corresponding β-amino alcohols, which were then used as eligible substrates in the synthesis of 5-methylmorpholin-2-ones via condensation with glyoxal in THF. The same procedure was applied for the preparation of novel 5(R)- and 5(S)-methylmorpholin-2-ones starting from the corresponding enantiopure 2-(hydroxymethyl)aziridines. Additionally, 2-(methoxymethyl)- and 2-(phenoxymethyl)aziridines were treated with LiAlH4 under microwave irradiation, giving rise to either isopropylamines or 1-methoxypropan-2-amines depending on the reaction conditions.

4,5-Disubstituted-1,3-oxazolidin-2-imine derivatives: A new class of orally bioavailable nitric oxide synthase inhibitor

In our search for a novel class of inducible nitric oxide synthase (iNOS) inhibitors, 1,3-oxazolidin-2-imine was found to weakly inhibit iNOS. Further modifications of this compound resulted in a remarkable increase in both the in vivo and in vitro inhibi