3217-93-4Relevant articles and documents
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Beckett,A.H. et al.
, p. 1531 - 1535 (1975)
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Chemoselective Synthesis of Amines from Ammonium Hydroxide and Hydroxylamine in Continuous Flow
Audubert, Clément,Bouchard, Alexanne,Mathieu, Gary,Lebel, Hélène
, p. 14203 - 14209 (2019/01/21)
The chemoselective amination of alkyl bromides and chlorides with aqueous ammonia and hydroxylamine was achieved in continuous flow to produce primary ammonium salts and hydroxylamines in high yields. An in-line workup was designed to isolate the corresponding primary amine, which was also telescoped in further reactions, such as acylation and Paal-Knorr pyrrole synthesis. Monosubstituted epoxides are also compatible with the reaction conditions.
VITAMIN D3 LACTAM DERIVATIVE
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Page/Page column 5, (2011/09/16)
Compound represented by formula (1) or a pharmaceutically acceptable solvate thereof, useful for treating or preventing Paget's disease of bone, hypercalcaemia, osteoporosis or asthma. (1) R1 represents a C1-C6 alkyl group