323195-82-0

Basic information

• Product Name: Ethyl (2E)-3-(2-methoxy-4-methylphenyl)but-2-enoate
• Synonyms: Ethyl (2E)-3-(2-methoxy-4-methylphenyl)but-2-enoate
• CAS NO: 323195-82-0
• Molecular Weight: 234.295
• Mol File: 323195-82-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Ethyl (2E)-3-(2-methoxy-4-methylphenyl)but-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl (2E)-3-(2-methoxy-4-methylphenyl)but-2-enoate(323195-82-0)
• EPA Substance Registry System: Ethyl (2E)-3-(2-methoxy-4-methylphenyl)but-2-enoate(323195-82-0)

Safety Data

• Hazardous Substances Data: 323195-82-0(Hazardous Substances Data)

Upstream product

• 311-46-6 ethyl 2-(dimethoxyphosphoryl)acetate 
• 35633-35-3 2-methoxy-4-methylacetophenone 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 6921-64-8 4'-hydroxy-2'-methylacetophenone 

Downstream Products

• 246037-79-6 (S)-3-(2-methoxy-4-methylphenyl)butanoic acid 
• 1195504-74-5 (E)-3-(2-methoxy-4-methylphenyl)but-2-enoic acid 
• 323195-81-9 (2E)-3-(2-Methoxy-4-methylphenyl)but-2-enal 
• 70878-71-6 (S)-curcuphenol 
• 1001912-82-8 (S)-3-(2-methoxy-4-methylphenyl)butyl 4-methyl-1-benzenesulfonate 
• 217301-18-3 (S)-(+)-Curcuphenol methyl ether 
• 323195-86-4 (3S)-3-(2-Methoxy-4-methylphenyl)butyl iodide 
• 217301-15-0 (3S)-3-(2-Methoxy-4-methylphenyl)butan-2-ol 
• 71841-56-0 ethyl 3-(2-methoxy-4-methylphenyl)butanoate 
• 175735-91-8 [4-(2-Methoxy-4-methyl-phenyl)-2-oxo-pentyl]-phosphonic acid dimethyl ester 
• 67895-75-4 (+/-)-parahigginone methyl ether 

Relevant articles and documents

Diastereoselective hydrogenation of α,β-unsaturated but-2-enamides to access the chiral 3-(p-tolyl) butanoic acids

An alternative methodology for the synthesis of chiral 3-(p-tolyl) butanoic acids is presented. This was accomplished through the diastereoselective hydrogenation reaction of different chiral N-3-(p-tolyl) but-2-enamides, using Pd/C in EtOH, to produce the corresponding chiral N-3-(p-tolyl) butanamides with high chemical yields and moderate diastereomeric ratios. Removal of the chiral auxiliary from N-3-(p-tolyl) butanamides gave the respective enantiomerically pure acids.

Baker's yeast-mediated enantioselective synthesis of the bisabolane sesquiterpenes (+)-curcuphenol, (+)-xanthorrhizol, (-)-curcuquinone and (+)-curcuhydroquinone

Fermenting baker's yeast converts the unsaturated aldehydes 5a-c into the saturated alcohols 6a-c, respectively. The microbial saturation of substrates adsorbed on a nonpolar resin proceeds in high chemical yields and shows complete enantioselectivity in the formation of the (S)-(+) isomers. Enantiopure 6a-c are versatile chiral building blocks for the synthesis of bisabolane sesquiterpenes. Their usefulness is shown in the preparation of (S)-(+)-curcuphenol, (S)-(+)-xanthorrhizol, (S)-(-)-curcuquinone and (S)-(+)-curcuhydroquinone. The Royal Society of Chemistry 2000.