32399-12-5

Basic information

• Product Name: 2-(Methylamino)pyridine-3-methanol
• Synonyms: [2-(Methylamino)-3-pyridyl]methanol;2-(METHYLAMINO)-3-PYRIDINEMETHANOL 98%;3-HYDROXYMETHYL 2-METHYLAMINO PYRIDINE;[2-(Methylamino)pyridin-3-yl]methanol;2-(Methylamino)pyridine-3-methanol;2-(N-Methylamino)-3-hydroxymethylpyridine;2-(MethylaMino)-3-PyridineMethanol
• CAS NO: 32399-12-5
• Molecular Formula: C₇H₁₀N₂O
• Molecular Weight: 138.17
• EINECS: 1308068-626-2
• Product Categories: Hydroxymethyl's;Pyridines;Heterocycle-Pyridine series
• Mol File: 32399-12-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 312.2 °C at 760 mmHg
• Flash Point: 142.6 °C
• Appearance: /
• Density: 1.191 g/cm³
• Vapor Pressure: 0.00023mmHg at 25°C
• Refractive Index: 1.613
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 13.63±0.10(Predicted)
• CAS DataBase Reference: 2-(Methylamino)pyridine-3-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methylamino)pyridine-3-methanol(32399-12-5)
• EPA Substance Registry System: 2-(Methylamino)pyridine-3-methanol(32399-12-5)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 32399-12-5(Hazardous Substances Data)

Usage

General Description

2-(Methylamino)pyridine-3-methanol is a chemical compound with the molecular formula C7H10N2O. It is also known as 2-(methylamino)picolin-3-ol and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. This chemical is a colorless to pale yellow liquid with a faint amine odor. It is soluble in water and organic solvents, and it is stable under normal conditions. 2-(Methylamino)pyridine-3-methanol is considered to be a versatile building block in organic synthesis and is used in the preparation of various drugs and other important compounds. It is important to handle this chemical with care and follow proper safety protocols when working with it.

InChI:InChI=1/C7H10N2O/c1-8-7-6(5-10)3-2-4-9-7/h2-4,10H,5H2,1H3,(H,8,9)

Upstream product

• 338990-71-9 methyl 2-formamidonicotinate 
• 232951-83-6 tert-butyl 2-chloropyridine-3-carboxylate 
• 2942-59-8 2-chloronicotinic acid 
• 49609-84-9 2-Chloronicotinoyl chloride 
• 338990-70-8 tert-butyl 2-(methylamino)pyridine-3-carboxylate 
• 32399-13-6 2-(methylamino)pyridine-3-carboxylic acid 

Downstream Products

• 1239164-58-9 3-oxo-1-cyclohexenyl 1-(ethylthiomethyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate 
• 1239164-10-3 1-(ethylthiomethyl)-3-(2-hydroxy-6-oxo-1-cyclohexenecarbonyl)-1,8-naphthyridin-2(1H)-one 
• 338990-31-1 N-methyl N-(3-[((N-tert-butoxycarbonyl-N-methylamino)acetoxy)methyl]pyridin-2-yl)carbamic acid (1-chloroethyl) ester 
• 127555-45-7 1-Methyl-3-phenylsulfanyl-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one 
• 128271-33-0 Methyl-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine 
• 338990-63-9 1-[[N-methyl-N-3-[(t-butoxycarbonylmethylamino)acetoxymethyl]pyridin-2-yl]carbamoyloxy]ethyl-1-[(2R,3R)-2-(2,5-difluorophenyl)-2-hydroxy-3-[4-(4-cyanophenyl)thiazol-2-yl]butyl]-1H-[1,2,4]triazol-4-ium chloride 

Relevant articles and documents

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INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE

The present invention provides a compound of formula (II): an inhibitor of indoleamine 2,3-dioxygenase (IDO), which may be used as medicaments for the treatment of proliferative disorders, such as cancer, viral infections and/or autoimmune diseases. Its prodrugs are disclosed.

RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES

Provided are 2-pyridone derivatives which have excellent herbicidal activity and exhibit high safety to useful crops and so on; salts thereof; and herbicides containing same. In more detail, 2-pyridone derivatives represented by general formula [I] or agrochemically acceptable salts thereof, and herbicides containing these compounds are provided. In general formula [I], X1 is an oxygen atom or a sulfur atom; X2, X3, and X4 are to each CH or N(O)m; m is an integer of 0 or 1; R1 is a hydrogen atom, a C1-12 alkyl group, or the like; R2 is a halogen atom, a cyano group, or the like; n is an integer of 0 to 4; R3 is a hydroxyl group, a halogen atom, or the like; A1 is C(R11R12); A2 is C(R13R14) or C═O; A3 is C(R15R16); and R11, R12, R13, R14, R15, and R16 are each independently a hydrogen atom or a C1-6 alkyl group.