3248-28-0

Basic information

• Product Name: Dipropionyl peroxide(in solution,content≤27%)
• Synonyms: Dipropionyl peroxide(in solution,content≤27%);dipropionyl peroxide;Propionyl peroxide.;dipropionyl peroxide, ;Bis(1-oxopropyl) peroxide;Bis(1-oxopropyl)peroxide;peroxypropionic acid propionyl ester;propanoyl propaneperoxoate
• CAS NO: 3248-28-0
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.1412
• EINECS: 221-828-0
• Mol File: 3248-28-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 200 °C
• Boiling Point: 185.74°C (rough estimate)
• Flash Point: 59.3°C
• Appearance: /
• Density: 1.0945 (rough estimate)
• Vapor Pressure: 1.6mmHg at 25°C
• Refractive Index: 1.4310 (estimate)
• CAS DataBase Reference: Dipropionyl peroxide(in solution,content≤27%)(CAS DataBase Reference)
• NIST Chemistry Reference: Dipropionyl peroxide(in solution,content≤27%)(3248-28-0)
• EPA Substance Registry System: Dipropionyl peroxide(in solution,content≤27%)(3248-28-0)

Safety Data

• RIDADR: 3117
• HazardClass: 5.2
• PackingGroup: II
• Hazardous Substances Data: 3248-28-0(Hazardous Substances Data)

Usage

Uses

Initiator in polymerization reactions, such as the high-pressure polymerization of ethylene.

Definition

Avail- able as a 25% solution in a high-boiling hydrocar- bon, flash p 125F (51.6C).

General Description

Available only as a 25% solution. Pure material poses a severe explosion hazard. Used as an initiator in polymerization reactions.

Air & Water Reactions

Highly flammable. May ignite spontaneously if exposed to air.

Reactivity Profile

Dipropionyl peroxide(in solution,content≤27%) is a good oxidizing agent. May cause ignition of organic compounds on contact . Reacts violently with strongly reduced material such as sulfides, nitrides, and hydrides. Many produce explosions or generate gases (toxic and nontoxic). Generally, dilute solutions (<70%) are safe, but the presence of a catalyst (often a transition metal such as cobalt, iron, manganese, nickel, or vanadium) as an impurity may even then cause rapid decomposition, a buildup of heat, and even an explosion. May become explosive when evaporated to dryness or near-dryness. May explode from heat, contamination or loss of temperature control.

Hazard

Strong oxidizing agent, may explode if shocked or heated.

Safety Profile

material explodes at room temperature. When heated to decomposition it emits acrid smoke and fumes. See also PEROXIDES.

InChI:InChI=1/C6H10O4/c1-3-5(7)9-10-6(8)4-2/h3-4H2,1-2H3

Upstream product

• 123-62-6 propionic acid anhydride 
• 928-49-4 hex-3-yne 
• 802294-64-0 propionic acid 

Downstream Products

• 100-71-0 2-Ethylpyridine 
• 536-75-4 4-Ethylpyridine 
• 1122-69-6 2-ethyl-6-methylpyridine 
• 536-88-9 4-ethyl-2-methyl-pyridine 
• 15072-32-9 2-ethyl-3,5-dimethoxy-[1,4]benzoquinone 
• 106-97-8 n-butane 
• 74-84-0 ethane 
• 74-85-1 ethene 
• 15719-64-9 methylammonium carbonate 
• 42860-89-9 1,1,2-trichloro-but-1-ene 
• 84-51-5 2-ethylanthraquinone 
• 24624-29-1 1-ethylanthracene-9,10-dione 
• 1185-39-3 2,2-dimethyl-n-valeric acid 
• 763-06-4 2,2-dimethyladipic acid 

Relevant articles and documents

Unnatural α-Amino Acid Synthesized through α-Alkylation of Glycine Derivatives by Diacyl Peroxides

We have developed a protocol for catalyst- and additive-free α-alkylation reactions of glycine derivatives with diacyl peroxides, which proceed by a pathway involving addition of alkyl radicals to imine intermediates. The diacyl peroxide substrate acts as both alkylation agent and oxidizing agent, which means it is atom-economical. It was applied to various glycine derivatives, dipeptides, and a 3,4-dihydroquinoxalin-2(1H)-one derivative and could be carried out on a gram scale, indicating its utility for late-stage functionalization.

Towards targeting anticancer drugs: Ruthenium(II)-arene complexes with biologically active naphthoquinone-derived ligand systems

Anticancer active metal complexes with biologically active ligands have the potential to interact with more than one biological target, which could help to overcome acquired and/or intrinsic resistance of tumors to small molecule drugs. In this paper we present the preparation of 2-hydroxy-[1,4]-naphthoquinone-derived ligands and their coordination to a RuII(η6-p-cymene)Cl moiety. The synthesis of oxime derivatives resulted in the surprising formation of nitroso-naphthalene complexes, as confirmed by X-ray diffraction analysis. The compounds were shown to be stable in aqueous solution but reacted with glutathione and ascorbic acid rather than undergoing reduction. One-electron reduction with pulse radiolysis revealed different behavior for the naphthoquinone and nitroso-naphthalene complexes, which was also observed in in vitro anticancer assays.

KINETICS OF ADDITION OF THE ETHYL RADICALS TO FLUOROETHYLENES IN HEPTANE AND ISOOCTANE

The thermal decomposition of propionyl peroxide in heptane and isooctane was used as a source of free ethyl radicals for kinetic investigations.The rate constants for the addition of C2H5. to ethylene, vinyl fluoride, vinylidene fluoride, trifluoroethylene, and tetrafluoroethylene in relation to the rate constants for the abstraction of a hydrogen atom from heptane at 65 deg C are 52.3, 24.0, 10, 84, and 1000 respectively.For ethylene, vinyl fluoride, and trifluoroethylene the relative addition rate constants were also determined in isooctane (178, 78, and 252).Itwas calculated that for the CH3., C2H5., and CF3. radicals the hydrogen abstraction rate from heptane is 3.3, 3.2, and 2.2 times higher respectively than from isooctane.In the investigated systems ethyl radicals exhibit stronger nucleophilic character than methyl radicals.