32568-59-5

Basic information

• Product Name: Phenol, 4-ethenyl-, benzoate
• Synonyms: 4-Benzoyloxystyrene;4-Ethenylphenyl benzoate;Benzoesaeure-(4-vinyl-phenylester);Benzoic acid, 4-ethenylphenol;Benzoic acid-(4-vinyl-phenyl ester);Benzoic acid--4-ethenylphenol (1:1);Phenol, 4-ethenyl-, benzoate
• CAS NO: 32568-59-5
• Molecular Formula: C15H12O2
• Molecular Weight: 224.259
• Mol File: 32568-59-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 76.5~75.5 °C
• CAS DataBase Reference: Phenol, 4-ethenyl-, benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-ethenyl-, benzoate(32568-59-5)
• EPA Substance Registry System: Phenol, 4-ethenyl-, benzoate(32568-59-5)

Safety Data

• Hazardous Substances Data: 32568-59-5(Hazardous Substances Data)

Upstream product

• 917-64-6 methyl magnesium iodide 
• 5339-06-0 4-formylphenyl benzoate 
• 98-88-4 benzoyl chloride 
• 2628-17-3 4-Vinylphenol 
• 2628-16-2 p-acetoxystyrene 
• 93-97-0 benzoic acid anhydride 
• 3132-15-8 p-ethylphenyl benzoate 
• 2156-04-9 4-Vinylphenylboronic acid 
• 65-85-0 benzoic acid 
• 75175-10-9 4-benzoyloxy-trans-cinnamic acid 

Downstream Products

• 133346-21-1 Benzoic acid 4-{3-[2,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-4,5-dihydro-isoxazol-5-yl}-phenyl ester 
• 99859-60-6 [4-(1,2-dibromo-ethyl)-phenyl]-(2,3-dibromo-propyl)-ether 
• 16215-47-7 3-(4-vinylphenyloxy)-1-propene 
• 69097-97-8 7,4'-dihydroxy-dihydroflavone 
• 133346-23-3 5-(4-benzoyloxyphenyl)-3-(2,4-dihydroxyphenyl)isoxazoline 
• 133360-50-6 3-(2,4-dihydroxyphenyl)-5-(4-hydroxyphenyl)isoxazoline 
• 961-29-5 isoliquirtigenin 
• 133346-24-4 1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4'-hydroxyphenyl)-1-propanone 
• 2628-17-3 4-Vinylphenol 

Relevant articles and documents

Site-Selective Acceptorless Dehydrogenation of Aliphatics Enabled by Organophotoredox/Cobalt Dual Catalysis

The value of catalytic dehydrogenation of aliphatics (CDA) in organic synthesis has remained largely underexplored. Known homogeneous CDA systems often require the use of sacrificial hydrogen acceptors (or oxidants), precious metal catalysts, and harsh reaction conditions, thus limiting most existing methods to dehydrogenation of non- or low-functionalized alkanes. Here we describe a visible-light-driven, dual-catalyst system consisting of inexpensive organophotoredox and base-metal catalysts for room-temperature, acceptorless-CDA (Al-CDA). Initiated by photoexited 2-chloroanthraquinone, the process involves H atom transfer (HAT) of aliphatics to form alkyl radicals, which then react with cobaloxime to produce olefins and H2. This operationally simple method enables direct dehydrogenation of readily available chemical feedstocks to diversely functionalized olefins. For example, we demonstrate, for the first time, the oxidant-free desaturation of thioethers and amides to alkenyl sulfides and enamides, respectively. Moreover, the system's exceptional site selectivity and functional group tolerance are illustrated by late-stage dehydrogenation and synthesis of 14 biologically relevant molecules and pharmaceutical ingredients. Mechanistic studies have revealed a dual HAT process and provided insights into the origin of reactivity and site selectivity.

Process for preparing substituted styrenes

Substituted styrenes are synthesized by a simple, low temperature technique. A protected phenol styrene is reacted with an acid anhydride, dicarbonate, a halogen substituted alkyl, or an acid chloride in the presence of base to form a carbonyl substituted styrene. Unexpected yield decrease due to distillation is avoided because the product is sufficiently pure to be used without such distillation.