32570-19-7

Basic information

• Product Name: 1H-Pyrrole, 1-(3-methoxyphenyl)-2,5-dimethyl-
• CAS NO: 32570-19-7
• Molecular Formula: C13H15NO
• Molecular Weight: 201.268
• Mol File: 32570-19-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 1-(3-methoxyphenyl)-2,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 1-(3-methoxyphenyl)-2,5-dimethyl-(32570-19-7)
• EPA Substance Registry System: 1H-Pyrrole, 1-(3-methoxyphenyl)-2,5-dimethyl-(32570-19-7)

Safety Data

• Hazardous Substances Data: 32570-19-7(Hazardous Substances Data)

Upstream product

• 555-03-3 3-nitroanisole 
• 1333-74-0 hydrogen 
• 110-13-4 2,5-hexanedione 
• 124-41-4 sodium methylate 
• 217314-37-9 1-(3-iodophenyl)-2,5-dimethyl-1H-pyrrole 
• 536-90-3 m-Anisidine 
• 626-01-7 3-Iodoaniline 
• 67-56-1 methanol 

Downstream Products

• 536-90-3 m-Anisidine 
• 700854-99-5 1-(3-methoxyphenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde 
• 1428183-55-4 C₂₂H₂₄N₂O₄ 

Relevant articles and documents

META SUBSTITUTED PHENYLPYRAZOLO- AND PHENYLPYRROLO- PYRIDAZINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

The present invention relates to meta substituted phenylpyrazolo-and phenylpyrrolo-pyridazine derivatives of formula (I) having dual pharmacological activity towards both the a28 subunit, in particular the a28-l subunit, of the voltage-gated calcium channel and the NET receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.

Cyclodextrin-based PNN supramolecular assemblies: a new class of pincer-type ligands for aqueous organometallic catalysis

Water-soluble cyclodextrins (CDs) bearing two nitrogen atoms as metal coordinating sites have been synthesized. An appropriate phosphane could be included within their cavity through the primary face to form self-assembled PNN supramolecular edifices. Once the PNN ligands were coordinated to platinum, the resulting complexes proved to be very effective as catalysts in a domino reaction, where a Pt-catalyzed reduction of nitrobenzene was followed by a Paal-Knorr pyrrole reaction. In the nitrobenzene reduction, the modified CDs acted both as first- and second-sphere ligands. Contrary to an acyclic glucopyranose-based NN ligand unable to interact with a phosphane ligand, the CD-based PNN ligands stabilized the catalytic species in water by supramolecular means. Interestingly, the product and the water-soluble Pt-catalyst could be recovered in two different phases once the reaction was complete.

An efficient synthesis of N-substituted pyrroles catalyzed by MgI2 etherate

We describe a convenient and useful procedure for the synthesis of various 2,5-dimethyl-N-substituted pyrrole derivatives by the addition of 2,5-hexadione with aromatic amines, heteroaromatic amines and aliphatic amines catalyzed by MgI2 etherate (MgI2·(OEt2)n) in good to excellent yields.