325988-94-1

Basic information

• Product Name: 1-[(1R,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-3-(isopropoxy-dimethyl-silanyl)-1-methyl-propyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one
• Synonyms: 1-[(1R,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-3-(isopropoxy-dimethyl-silanyl)-1-methyl-propyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one
• CAS NO: 325988-94-1
• Molecular Weight: 528.634
• Mol File: 325988-94-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(1R,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-3-(isopropoxy-dimethyl-silanyl)-1-methyl-propyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(1R,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-3-(isopropoxy-dimethyl-silanyl)-1-methyl-propyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one(325988-94-1)
• EPA Substance Registry System: 1-[(1R,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-3-(isopropoxy-dimethyl-silanyl)-1-methyl-propyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one(325988-94-1)

Safety Data

• Hazardous Substances Data: 325988-94-1(Hazardous Substances Data)

Upstream product

• 325989-28-4 1-(2,2-diethoxy-ethyl)-3-(4-tetrazol-1-yl-phenyl)-urea 
• 181870-66-6 1-[4-(1H-1-tetrazolyl)phenyl]-2(1H,3H)-imidazolone 
• 217654-45-0 phenyl 4-(1H-1-tetrazolyl)phenylcarbamate 
• 350-46-9 4-Fluoronitrobenzene 
• 14213-13-9 4-tetrazol-1-yl-phenylamine 
• 122588-50-5 (dimethylisopropoxysilyl)methylmagnesium chloride 
• 325988-93-0 1-[(R)-2-(2,4-Difluoro-phenyl)-1-methyl-2-oxo-ethyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one 

Downstream Products

• 181870-69-9 1-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2(1H,3H)-imidazolone 
• 181869-54-5 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-imidazolidinone 
• 181869-53-4 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-(1H,3H)-imidazolone 
• 325988-95-2 1-[(1R,2S)-2-(2,4-Difluoro-phenyl)-2,3-dihydroxy-1-methyl-propyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one 

Relevant articles and documents

Optically active antifungal azoles. X. Synthesis and antifungal activity of N-[4-(azolyl)phenyl]- and N-[4-(azolylmethyl)phenyl]-N′-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy -1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-azolones

New optically active antifungal azoles, N-[4-(azolyl)phenyl]- and N-[4-(azolylmethyl)phenyl]-N′-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy -1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]azolones (1, 2, 3), were prepared in a stereocontrolled manner. Compounds 1