181870-69-9

Upstream product

• 14213-13-9 4-tetrazol-1-yl-phenylamine 
• 150802-96-3 (2S,3R)-3-(2,4-Difluorophenyl)-3,4-epoxy-2-butanol 
• 181870-66-6 1-[4-(1H-1-tetrazolyl)phenyl]-2(1H,3H)-imidazolone 
• 325988-94-1 1-[(1R,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-3-(isopropoxy-dimethyl-silanyl)-1-methyl-propyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one 
• 325988-93-0 1-[(R)-2-(2,4-Difluoro-phenyl)-1-methyl-2-oxo-ethyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one 
• 325989-28-4 1-(2,2-diethoxy-ethyl)-3-(4-tetrazol-1-yl-phenyl)-urea 
• 217654-45-0 phenyl 4-(1H-1-tetrazolyl)phenylcarbamate 
• 350-46-9 4-Fluoronitrobenzene 
• 126918-33-0 (1S)-1-<(2R)-2-(2,4-difluorophenyl)-2-oxiranyl>ethanol 
• 124-63-0 methanesulfonyl chloride 
• 325988-95-2 1-[(1R,2S)-2-(2,4-Difluoro-phenyl)-2,3-dihydroxy-1-methyl-propyl]-3-(4-tetrazol-1-yl-phenyl)-1,3-dihydro-imidazol-2-one 

Downstream Products

• 181869-53-4 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-(1H,3H)-imidazolone 
• 181869-54-5 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-imidazolidinone 

Relevant academic research and scientific papers

Azole compounds, their production and use

PCT No. PCT/JP96/00325 Sec. 371 Date Oct. 17, 1996 Sec. 102(e) Date Oct. 17, 1996 PCT Filed Feb. 15, 1996 PCT Pub. No. WO96/25410 PCT Pub. Date Aug. 20, 1996The present invention provides an azole compound represented by the formula (I): wherein Ar is an

Optically active antifungal azoles. X. Synthesis and antifungal activity of N-[4-(azolyl)phenyl]- and N-[4-(azolylmethyl)phenyl]-N′-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy -1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-azolones

New optically active antifungal azoles, N-[4-(azolyl)phenyl]- and N-[4-(azolylmethyl)phenyl]-N′-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy -1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]azolones (1, 2, 3), were prepared in a stereocontrolled manner. Compounds 1