32664-13-4

Basic information

• Product Name: 2-(2-BROMOPHENYL)-4,5-DIHYDRO-4,4-DIMETHYLOXAZOLE
• Synonyms: 2-(2-BROMOPHENYL)-4,5-DIHYDRO-4,4-DIMETHYLOXAZOLE;AKOS AKM01077
• CAS NO: 32664-13-4
• Molecular Formula: C₁₁H₁₂BrNO
• Molecular Weight: 254.12
• Mol File: 32664-13-4.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 316.4°C at 760 mmHg
• Flash Point: 145.2°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 0.000762mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 2-(2-BROMOPHENYL)-4,5-DIHYDRO-4,4-DIMETHYLOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-BROMOPHENYL)-4,5-DIHYDRO-4,4-DIMETHYLOXAZOLE(32664-13-4)
• EPA Substance Registry System: 2-(2-BROMOPHENYL)-4,5-DIHYDRO-4,4-DIMETHYLOXAZOLE(32664-13-4)

Safety Data

• Hazardous Substances Data: 32664-13-4(Hazardous Substances Data)

Usage

General Description

2-(2-Bromophenyl)-4,5-dihydro-4,4-dimethyloxazole, also known as BAC, is a commonly used biocide and antimicrobial agent. It is a white to light yellow crystalline powder with a molecular formula of C11H12BrNO and a molecular weight of 242.12 g/mol. BAC is widely used in a variety of applications, including disinfectants, pesticides, and preservatives for personal care products. It is effective against a broad spectrum of microorganisms, including bacteria, fungi, and algae, making it a versatile and reliable chemical for controlling microbial growth. Despite its antimicrobial properties, BAC has also been associated with health and environmental risks, and its use is regulated in many countries to ensure safe handling and disposal.

InChI:InChI=1/C11H12BrNO/c1-11(2)7-14-10(13-11)8-5-3-4-6-9(8)12/h3-6H,7H2,1-2H3

Upstream product

• 2042-37-7 o-cyanobromobenzene 
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• 88-65-3 2-bromobenzoic-acid 
• 54596-21-3 2-bromo-N-(2-hydroxy-1,1-dimethylethyl)benzamide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 7154-66-7 2-bromobenzoic acid chloride 

Downstream Products

• 54596-15-5 1-benzyl-3-[2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-piperidin-3-ol 
• 19312-06-2 4,5-dihydro-4,4-dimethyl-2-phenoxazole 
• 956031-25-7 4,4-dimethyl-2-[ortho-(2,4,6-trimethylphenylamino)phenyl]-2-oxazoline 
• 956031-26-8 4,4-dimethyl-2-[ortho-(4,6-diisoprophylphenylamino)phenyl]-2-oxazoline 
• 56658-21-0 1-benzyl-3-[2-(4,4-dimethyl-2-oxazolin-2-yl)phenyl]-3-hydroxypyrrolidine 
• 1010691-43-6 (S)-N-[2-[(4,4-dimethyl)-4,5-dihydro-2-oxazolyl]phenyl]-S-methyl-S-phenylsulfoximine 
• 1115095-62-9 cis-4,4-dimethyl-2-[2-(2-phenylvinyl)phenyl]-4,5-dihydrooxazole 
• 84392-32-5 4,4-dimethyl-2-(4'-methyl-biphenyl-2-yl)-4,5-dihydrooxazole 
• 1241912-45-7 C₂₈H₃₀N₂O₂ 
• 1352090-05-1 NC(CH₃)2CH₂OCC₆H₄NHC₂H₄N(CH₃)2 
• 1609493-12-0 (Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-2-methylpropan-1-ol 
• 1609493-20-0 C₃₁H₃₀Cl₂N₂O₄Pd 
• 88440-92-0 2-<2-(1-Hydroxybutyl)phenyl>-4,4-dimethyloxazoline 
• 60049-53-8 3-(4-methoxynaphthalen-1-yl)isobenzofuran-1(3H)-one 

Relevant articles and documents

Copper Photosensitizers Containing P^N Ligands and Their Influence on Photoactivity and Stability

Driven by the intention to improve classic heteroleptic copper photosensitizers two novel Cu(I) complexes applying a hetero-bidentate P^N ligand were prepared. A combined photophysical, electrochemical, and theoretical study gives insights into structure–activity relationships and revealed an increased absorptivity. Both complexes were tested for the light-driven production of H2.

Sulfoxide ligand metal catalyzed oxidation of olefins

The enantioselective synthesis of isochroman motifs has been accomplished via Pd(II)-catalyzed allylic C—H oxidation from terminal olefin precursors. Critical to the success of this goal was the development and utilization of a novel chiral aryl sulfoxide-oxazoline (ArSOX) ligand. The allylic C—H oxidation reaction proceeds with the broadest scope and highest levels asymmetric induction reported to date (avg. 92% ee, 13 examples ≥90% ee). Additionally, C(sp3)-N fragment coupling reaction between abundant terminal olefins and N-triflyl protected aliphatic and aromatic amines via Pd(II)/sulfoxide (SOX) catalyzed intermolecular allylic C—H amination is disclosed. A range of 52 allylic amines are furnished in good yields (avg. 76%) and excellent regio- and stereoselectivity (avg. >20:1 linear:branched, >20:1 E:Z). For the first time, a variety of singly activated aromatic and aliphatic nitrogen nucleophiles, including ones with stereochemical elements, can be used in fragment coupling stiochiometries for intermolecular C—H amination reactions.

C-H to C-N Cross-Coupling of Sulfonamides with Olefins

Cross-coupling of nitrogen with hydrocarbons under fragment coupling conditions stands to significantly impact chemical synthesis. Herein, we disclose a C(sp3)-N fragment coupling reaction between terminal olefins and N-triflyl protected aliphatic and aromatic amines via Pd(II)/SOX (sulfoxide-oxazoline) catalyzed intermolecular allylic C-H amination. A range of (56) allylic amines are furnished in good yields (avg. 75%) and excellent regio- and stereoselectivity (avg. >20:1 linear:branched, >20:1 E:Z). Mechanistic studies reveal that the SOX ligand framework is effective at promoting functionalization by supporting cationic π-allyl Pd.