32691-58-0

Upstream product

• 143-33-9 sodium cyanide 
• 74502-83-3 2-(Chloromethyl)-4,6-dimethylpyrimidine 
• 123-54-6 acetylacetone 
• 4472-44-0 2-chloro-4,6-dimethylpyrimidine 
• 1224935-98-1 α-cyano-4,6-dimethyl-2-pyrimidineacetic acid tert-butyl ester 
• 54198-72-0 (4,6-dimethylpyrimidin-2-yl)methanol 
• 1558-17-4 4,6-dimethylpyrimidine 
• 90090-75-8 2-(carbamoylmethyl)-4,6-dimethylpyrimidine 
• 108-24-7 acetic anhydride 
• 84041-07-6 2-Amino-5,7-dimethylisoxazolo<2,3-a>pyrimidinium Chloride 

Downstream Products

• 77204-23-0 α-(4,6-dimethyl-2-pyrimidinyl)cinnamonitrile 
• 1224936-02-0 5-amino-4-(4,6-dimethyl-2-pyrimidinyl)-2,3-dihydro-1-phenylpyrrol-2-one 
• 1224936-06-4 5-amino-4-(4,6-dimethyl-2-pyrimidinyl)-2,3-dihydro-1-(4-methylphenyl)pyrrol-2-one 
• 1224936-04-2 5-amino-1-(4-chlorophenyl)-4-(4,6-dimethyl-2-pyrimidinyl)-2,3-dihydropyrrol-2-one 
• 1224936-05-3 5-amino-4-(4,6-dimethyl-2-pyrimidinyl)-2,3-dihydro-1-(4-methoxyphenyl)pyrrol-2-one 
• 1258979-67-7 C₂₄H₁₅ClN₂O₄ 
• 1258979-61-1 3-(4-chlorophenoxy)-9-(4,6-dimethylpyrimidin-2-yl)-8-imino-2-methyl-4H,8H-pyrano[2,3-f]chromen-4-one 
• 1258979-63-3 C₂₅H₁₇ClN₂O₅ 
• 77204-22-9 α-(4,6-dimethyl-2-pyrimidinyl)-β-phenylpropionitrile 
• 783325-61-1 4,6-dimethyl-2-methylaminonicotinonitrile 
• 77204-39-8 2-Benzyl-2-(4,6-dimethyl-pyrimidin-2-yl)-3-phenyl-propionitrile 

Relevant academic research and scientific papers

Investigation of the nucleophilic rearrangement of 2-(cyanomethyl)-1,4,6- trimethylpyrimidinium iodide into 4,6-dimethyl-2-methylaminonicotinic acid nitrile

2-(Cyanomethyl)-1,4,6-trimethylpyrimidinium iodide is rearranged into 4,6-dimethyl-2-methylaminonicotinic acid nitrile by interaction with alcoholic solutions of sodium ethylate, methylamine, and also glycine and β-alanine ethyl esters. This conversion was also observed for the first time for pyrimidinium salts during the process of recording 1H NMR spectra in CD3OD solution containing CD3ONa. After the rearrangement deuterium exchange of the protons of the pyridine ring methyl groups was noted spectrally. It was demonstrated experimentally that for carrying out and completing the recyclization a quantity of nucleophilic reagent must convert the molar equivalent quantity of pyridinium salt.

RESIN COMPOSITION AND MOLDED ARTICLE

The invention contains a resin and a near infrared fluorescent material which is one type or two or more types of compounds selected from General Formulas (I1) to (I4) and has a maximum fluorescence wavelength of 650 nm or longer. In Formulas, Ra and Rb, Rc and Rd, Rh and Ri, and Rj and Rk form rings together with the nitrogen atom to which Ra, Rc, Rh, and Rj are bonded; Re and Rf represent a halogen atom or an oxygen atom; each of Rl, Rm, Rn, and Ro independently represents a halogen atom, a C1-20 alkyl group, a C1-20 alkoxy group, an aryl group, or a heteroaryl group; Rg, Rr, and Rs represent a hydrogen atom or an electron withdrawing group; and each of Rp and Rq independently represents a hydrogen atom, a halogen atom, a C1-20 alkyl group, a C1-20 alkoxy group, an aryl group, or a heteroaryl group.

Synthesis of 3-(pyrimidinyl)pyrrole derivatives

Alkylation of 4,6-dimethyl-2-pyrimidineacetonitrile and 2,6-dimethyl-4-pyrimidineacetonitrile with chloroacetic acid anilides was shown to give 5-amino-4-(4,6-dimethyl-2-pyrimidinyl)-2,3-dihydro-1-arylpyrrol-2-ones and 5-amino-4-(2,6-dimethyl-4-pyrimidiny

Pyrrolopyrrole cyanine dyes: A new class of near-Infrared dyes and fluorophores

Pyrrolopyrrole cyanine (PPCy) dyes are presented as a novel class of near-infrared (NIR) chromophores, which are synthesized in a condensation reaction of diketopyrrolopyr-role with heteroarylacetonitrile compounds. Their optical properties are marked by strong and narrow-band NIR absorptions. Complexation prod-ucts with BF2 and BPh2 show strong NIR fluorescence and hardly any ab-sorption in the visible range. We syn-thesized a series of new PPCys that differ only in the heterocyclic peripheral groups of the chromophore. With this strategy, the absorption spectra can be tuned between 684 and 864 nm, while high fluorescence quantum yields are maintained. The influence of the heterocycle on the optical properties of the dyes is discussed.

Molecular Rearrangements. Synthesis, Stability, and Rearrangements of 2-Imino-2H-isoxazolopyrimidines and 2-Aminoisoxazolopyrimidinium Salts

2-Amino derivatives of isoxazolopyrimidinium salts were prepared by the condensation of 3,5-diaminoisoxazole with acetylacetone and benzoylacetone, respectively.The free base, e.g., 2-amino-2H-isoxazolopyrimidine system, was found to be unst

Studies on Pyrimidine Derivatives. XX. Synthetic Utility of Hydroxymethylpyrimidines and Related Compounds

The conversion of a hydroxymethyl group at the 2- or 4-position of simple pyrimidines to a chloromethyl, cyanomethyl, ethoxycarbonylmethyl, or formyl group is described.Various pyrimidines having an olefinic side chain were also synthesized via Witting reagents derived from chloromethylpyrimidines.Keywords - hydroxymethylation; chloromethylpyrimidine; cyanomethylpyrimidine; pyrimidinecarbaldehyde; Witting reaction