54198-72-0

Basic information

• Product Name: 2-Pyrimidinemethanol, 4,6-dimethyl- (9CI)
• Synonyms: 2-Pyrimidinemethanol, 4,6-dimethyl- (9CI);(4,6-dimethylpyrimidin-2-yl)methanol
• CAS NO: 54198-72-0
• Molecular Formula: C₇H₁₀N₂O
• Molecular Weight: 138.1671
• Product Categories: PYRIMIDINE
• Mol File: 54198-72-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 87-88 °C
• Boiling Point: 235.1±28.0 °C(Predicted)
• Appearance: /
• Density: 1.130±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 13.75±0.10(Predicted)
• CAS DataBase Reference: 2-Pyrimidinemethanol, 4,6-dimethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrimidinemethanol, 4,6-dimethyl- (9CI)(54198-72-0)
• EPA Substance Registry System: 2-Pyrimidinemethanol, 4,6-dimethyl- (9CI)(54198-72-0)

Safety Data

• Hazardous Substances Data: 54198-72-0(Hazardous Substances Data)

Usage

General Description

2-Pyrimidinemethanol, 4,6-dimethyl- (9CI) is a chemical compound with the molecular formula C7H10N2O. It is a derivative of pyrimidine and contains a hydroxyl group attached to the methylene carbon. 2-Pyrimidinemethanol, 4,6-dimethyl- (9CI) is a colorless liquid with a molecular weight of 138.17 g/mol. It is mainly used in the synthesis of pharmaceuticals and agrochemicals. Additionally, it has potential applications in the field of organic chemistry as a building block for the creation of complex molecules. 2-Pyrimidinemethanol, 4,6-dimethyl- (9CI) may also have other industrial uses, such as in the production of specialty chemicals and other commercial products.

Upstream product

• 4472-44-0 2-chloro-4,6-dimethylpyrimidine 
• 27427-89-0 methyl 4,6-dimethylpyrimidine-2-carboxylate 
• 91148-70-8 Acetic acid 4,6-dimethyl-pyrimidin-2-ylmethyl ester 
• 74502-83-3 2-(Chloromethyl)-4,6-dimethylpyrimidine 
• 1558-17-4 4,6-dimethylpyrimidine 
• 67-56-1 methanol 

Downstream Products

• 27427-90-3 4,6-dimethyl-2-pyrimidinecarboxaldehyde 
• 74502-83-3 2-(Chloromethyl)-4,6-dimethylpyrimidine 
• 77204-31-0 4,6-dimethyl-2-trans-styrylpyrimidine 
• 77204-30-9 (4,6-dimethyl-2-pyrimidinylmethyl)triphenylphosphonium chloride 
• 77204-39-8 2-Benzyl-2-(4,6-dimethyl-pyrimidin-2-yl)-3-phenyl-propionitrile 
• 77204-22-9 α-(4,6-dimethyl-2-pyrimidinyl)-β-phenylpropionitrile 
• 77204-23-0 α-(4,6-dimethyl-2-pyrimidinyl)cinnamonitrile 
• 77204-33-2 2-cyclohexylidenemethyl-4,6-dimethylpyrimidine 
• 32691-58-0 2-(cyanomethylene)-4,6-dimethylpyrimidine 

Relevant articles and documents

IMIDAZOTRIAZINONE COMPOUNDS

The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9 and pharmaceutically acceptable salt thereof. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans.

Studies on Pyrimidine Derivatives. XX. Synthetic Utility of Hydroxymethylpyrimidines and Related Compounds

The conversion of a hydroxymethyl group at the 2- or 4-position of simple pyrimidines to a chloromethyl, cyanomethyl, ethoxycarbonylmethyl, or formyl group is described.Various pyrimidines having an olefinic side chain were also synthesized via Witting reagents derived from chloromethylpyrimidines.Keywords - hydroxymethylation; chloromethylpyrimidine; cyanomethylpyrimidine; pyrimidinecarbaldehyde; Witting reaction